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Quantitative and systematic NMR measurements of sequence-dependent A-T Hoogsteen dynamics uncovers unique conformational specificity in the DNA double helix.
bioRxiv [Preprint]. 2024 May 15:2024.05.15.594415. doi: 10.1101/2024.05.15.594415.
bioRxiv. 2024.
PMID: 38798635
Free PMC article.
Preprint.
NMR measurements of transient low-populated tautomeric and anionic Watson-Crick-like G·T/U in RNA:DNA hybrids: implications for the fidelity of transcription and CRISPR/Cas9 gene editing.
Szekely O, Rangadurai AK, Gu S, Manghrani A, Guseva S, Al-Hashimi HM.
Szekely O, et al. Among authors: manghrani a.
Nucleic Acids Res. 2024 Mar 21;52(5):2672-2685. doi: 10.1093/nar/gkae027.
Nucleic Acids Res. 2024.
PMID: 38281263
Free PMC article.
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NMR measurements of transient low-populated tautomeric and anionic Watson-Crick-like G·T/U in RNA:DNA hybrids: Implications for the fidelity of transcription and CRISPR/Cas9 gene editing.
Szekely O, Rangadurai AK, Gu S, Manghrani A, Guseva S, Al-Hashimi HM.
Szekely O, et al. Among authors: manghrani a.
bioRxiv [Preprint]. 2023 Aug 24:2023.08.24.554670. doi: 10.1101/2023.08.24.554670.
bioRxiv. 2023.
PMID: 37662220
Free PMC article.
Updated.
Preprint.
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Author Correction: RNA conformational propensities determine cellular activity.
Ken ML, Roy R, Geng A, Ganser LR, Manghrani A, Cullen BR, Schulze-Gahmen U, Herschlag D, Al-Hashimi HM.
Ken ML, et al. Among authors: manghrani a.
Nature. 2023 Jun;618(7967):E35. doi: 10.1038/s41586-023-06286-z.
Nature. 2023.
PMID: 37296211
No abstract available.
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RNA conformational propensities determine cellular activity.
Ken ML, Roy R, Geng A, Ganser LR, Manghrani A, Cullen BR, Schulze-Gahmen U, Herschlag D, Al-Hashimi HM.
Ken ML, et al. Among authors: manghrani a.
Nature. 2023 May;617(7962):835-841. doi: 10.1038/s41586-023-06080-x. Epub 2023 May 17.
Nature. 2023.
PMID: 37198487
Free PMC article.
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Dynamic basis for dA•dGTP and dA•d8OGTP misincorporation via Hoogsteen base pairs.
Gu S, Szymanski ES, Rangadurai AK, Shi H, Liu B, Manghrani A, Al-Hashimi HM.
Gu S, et al. Among authors: manghrani a.
Nat Chem Biol. 2023 Jul;19(7):900-910. doi: 10.1038/s41589-023-01306-5. Epub 2023 Apr 24.
Nat Chem Biol. 2023.
PMID: 37095237
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Hoogsteen base pairs increase the susceptibility of double-stranded DNA to cytotoxic damage.
Xu Y, Manghrani A, Liu B, Shi H, Pham U, Liu A, Al-Hashimi HM.
Xu Y, et al. Among authors: manghrani a.
J Biol Chem. 2020 Nov 20;295(47):15933-15947. doi: 10.1074/jbc.RA120.014530. Epub 2020 Sep 10.
J Biol Chem. 2020.
PMID: 32913127
Free PMC article.
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