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Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau pathologies.
Montoliu-Gaya L, Benedet AL, Tissot C, Vrillon A, Ashton NJ, Brum WS, Lantero-Rodriguez J, Stevenson J, Nilsson J, Sauer M, Rahmouni N, Brinkmalm G, Lussier FZ, Pascoal TA, Skoog I, Kern S, Zetterberg H, Paquet C, Gobom J, Rosa-Neto P, Blennow K. Montoliu-Gaya L, et al. Among authors: brum ws. Nat Aging. 2023 Jun;3(6):661-669. doi: 10.1038/s43587-023-00405-1. Epub 2023 Apr 27. Nat Aging. 2023. PMID: 37198279 Free PMC article.
Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology.
Povala G, Bellaver B, De Bastiani MA, Brum WS, Ferreira PCL, Bieger A, Pascoal TA, Benedet AL, Souza DO, Araujo RM, Zatt B, Rosa-Neto P, Zimmer ER; for the Alzheimer’s Disease Neuroimaging Initiative. Povala G, et al. Among authors: brum ws. Cell Biosci. 2021 Dec 11;11(1):204. doi: 10.1186/s13578-021-00712-3. Cell Biosci. 2021. PMID: 34895338 Free PMC article.
The accuracy and robustness of plasma biomarker models for amyloid PET positivity.
Benedet AL, Brum WS, Hansson O; Alzheimer’s Disease Neuroimaging Initiative; Karikari TK, Zimmer ER, Zetterberg H, Blennow K, Ashton NJ. Benedet AL, et al. Among authors: brum ws. Alzheimers Res Ther. 2022 Feb 7;14(1):26. doi: 10.1186/s13195-021-00942-0. Alzheimers Res Ther. 2022. PMID: 35130933 Free PMC article.
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease.
Ashton NJ, Benedet AL, Pascoal TA, Karikari TK, Lantero-Rodriguez J, Brum WS, Mathotaarachchi S, Therriault J, Savard M, Chamoun M, Stoops E, Francois C, Vanmechelen E, Gauthier S, Zimmer ER, Zetterberg H, Blennow K, Rosa-Neto P. Ashton NJ, et al. Among authors: brum ws. EBioMedicine. 2022 Feb;76:103836. doi: 10.1016/j.ebiom.2022.103836. Epub 2022 Feb 12. EBioMedicine. 2022. PMID: 35158308 Free PMC article.
A three-range approach enhances the prognostic utility of CSF biomarkers in Alzheimer's disease.
Brum WS, de Bastiani MA, Bieger A, Therriault J, Ferrari-Souza JP, Benedet AL, Saha-Chaudhuri P, Souza DO, Ashton NJ, Zetterberg H, Pascoal TA, Karikari T, Blennow K, Rosa-Neto P, Zimmer ER; Alzheimer's Disease Neuroimaging Initiative (ADNI). Brum WS, et al. Alzheimers Dement (N Y). 2022 Mar 13;8(1):e12270. doi: 10.1002/trc2.12270. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35310530 Free PMC article.
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility.
Karikari TK, Ashton NJ, Brinkmalm G, Brum WS, Benedet AL, Montoliu-Gaya L, Lantero-Rodriguez J, Pascoal TA, Suárez-Calvet M, Rosa-Neto P, Blennow K, Zetterberg H. Karikari TK, et al. Among authors: brum ws. Nat Rev Neurol. 2022 Jul;18(7):400-418. doi: 10.1038/s41582-022-00665-2. Epub 2022 May 18. Nat Rev Neurol. 2022. PMID: 35585226 Review.
Test-retest variability of plasma biomarkers in Alzheimer's disease and its effects on clinical prediction models.
Cullen NC, Janelidze S, Mattsson-Carlgren N, Palmqvist S, Bittner T, Suridjan I, Jethwa A, Kollmorgen G, Brum WS, Zetterberg H, Blennow K, Stomrud E, Hansson O. Cullen NC, et al. Among authors: brum ws. Alzheimers Dement. 2022 Jun 14:10.1002/alz.12706. doi: 10.1002/alz.12706. Online ahead of print. Alzheimers Dement. 2022. PMID: 35699240 Free PMC article.
Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer's disease.
Ferrari-Souza JP, Ferreira PCL, Bellaver B, Tissot C, Wang YT, Leffa DT, Brum WS, Benedet AL, Ashton NJ, De Bastiani MA, Rocha A, Therriault J, Lussier FZ, Chamoun M, Servaes S, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, Klunk WE, Tudorascu DL, Cohen AD, Villemagne VL, Gauthier S, Blennow K, Zetterberg H, Souza DO, Karikari TK, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Among authors: brum ws. Mol Psychiatry. 2022 Nov;27(11):4781-4789. doi: 10.1038/s41380-022-01716-2. Epub 2022 Aug 10. Mol Psychiatry. 2022. PMID: 35948658 Free PMC article.
Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau immunoassays.
Ashton NJ, Puig-Pijoan A, Milà-Alomà M, Fernández-Lebrero A, García-Escobar G, González-Ortiz F, Kac PR, Brum WS, Benedet AL, Lantero-Rodriguez J, Day TA, Vanbrabant J, Stoops E, Vanmechelen E, Triana-Baltzer G, Moughadam S, Kolb H, Ortiz-Romero P, Karikari TK, Minguillon C, Hernández Sánchez JJ, Navalpotro-Gómez I, Grau-Rivera O, María Manero R, Puente-Periz V, de la Torre R, Roquer J, Dage JL, Zetterberg H, Blennow K, Suárez-Calvet M. Ashton NJ, et al. Among authors: brum ws. Alzheimers Dement. 2023 May;19(5):1913-1924. doi: 10.1002/alz.12841. Epub 2022 Nov 12. Alzheimers Dement. 2023. PMID: 36370462 Free PMC article.
39 results