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Chimeric TIM-4 receptor-modified T cells targeting phosphatidylserine mediates both cytotoxic anti-tumor responses and phagocytic uptake of tumor-associated antigen for T cell cross-presentation.
Mol Ther. 2023 Jul 5;31(7):2132-2153. doi: 10.1016/j.ymthe.2023.05.009. Epub 2023 May 16.
Mol Ther. 2023.
PMID: 37194236
Free article.
Therapeutic Targeting of TIM-4-L with Engineered T Cells for Acute Myeloid Leukemia.
Cieniewicz B, Oliveira E, Saxton M, Torabi D, Bhatta A, Kukutla P, Arballo A, Yang Z, Yu B, Fate M, Ning H, Corey L, Maiti A, Corey D.
Cieniewicz B, et al. Among authors: arballo a.
Clin Cancer Res. 2024 May 1;30(9):1878-1888. doi: 10.1158/1078-0432.CCR-23-3044.
Clin Cancer Res. 2024.
PMID: 38451195
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