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Personalised versus standard dosimetry approach of selective internal radiation therapy in patients with locally advanced hepatocellular carcinoma (DOSISPHERE-01): a randomised, multicentre, open-label phase 2 trial.
Garin E, Tselikas L, Guiu B, Chalaye J, Edeline J, de Baere T, Assenat E, Tacher V, Robert C, Terroir-Cassou-Mounat M, Mariano-Goulart D, Amaddeo G, Palard X, Hollebecque A, Kafrouni M, Regnault H, Boudjema K, Grimaldi S, Fourcade M, Kobeiter H, Vibert E, Le Sourd S, Piron L, Sommacale D, Laffont S, Campillo-Gimenez B, Rolland Y; DOSISPHERE-01 Study Group. Garin E, et al. Among authors: laffont s. Lancet Gastroenterol Hepatol. 2021 Jan;6(1):17-29. doi: 10.1016/S2468-1253(20)30290-9. Epub 2020 Nov 7. Lancet Gastroenterol Hepatol. 2021. PMID: 33166497 Free article. Clinical Trial.
Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis.
Chi L, Liu C, Gribonika I, Gschwend J, Corral D, Han SJ, Lim AI, Rivera CA, Link VM, Wells AC, Bouladoux N, Collins N, Lima-Junior DS, Enamorado M, Rehermann B, Laffont S, Guéry JC, Tussiwand R, Schneider C, Belkaid Y. Chi L, et al. Among authors: laffont s. Science. 2024 Apr 12;384(6692):eadk6200. doi: 10.1126/science.adk6200. Epub 2024 Apr 12. Science. 2024. PMID: 38574174
Monocytes are the main source of STING-mediated IFN-α production.
Congy-Jolivet N, Cenac C, Dellacasagrande J, Puissant-Lubrano B, Apoil PA, Guedj K, Abbas F, Laffont S, Sourdet S, Guyonnet S, Nourhashemi F, Guéry JC, Blancher A. Congy-Jolivet N, et al. Among authors: laffont s. EBioMedicine. 2022 Jun;80:104047. doi: 10.1016/j.ebiom.2022.104047. Epub 2022 May 10. EBioMedicine. 2022. PMID: 35561451 Free PMC article.
Targeting androgen signaling in ILC2s protects from IL-33-driven lung inflammation, independently of KLRG1.
Blanquart E, Mandonnet A, Mars M, Cenac C, Anesi N, Mercier P, Audouard C, Roga S, Serrano de Almeida G, Bevan CL, Girard JP, Pelletier L, Laffont S, Guéry JC. Blanquart E, et al. Among authors: laffont s. J Allergy Clin Immunol. 2022 Jan;149(1):237-251.e12. doi: 10.1016/j.jaci.2021.04.029. Epub 2021 May 5. J Allergy Clin Immunol. 2022. PMID: 33964300 Free article.
Sex hormone regulation of innate lymphoid cells.
Blanquart E, Laffont S, Guéry JC. Blanquart E, et al. Among authors: laffont s. Biomed J. 2021 Apr;44(2):144-156. doi: 10.1016/j.bj.2020.11.007. Epub 2020 Nov 18. Biomed J. 2021. PMID: 33888441 Free PMC article. Review.
TLR7 dosage polymorphism shapes interferogenesis and HIV-1 acute viremia in women.
Azar P, Mejía JE, Cenac C, Shaiykova A, Youness A, Laffont S, Essat A, Izopet J, Passaes C, Müller-Trutwin M, Delobel P, Meyer L, Guéry JC. Azar P, et al. Among authors: laffont s. JCI Insight. 2020 Jun 18;5(12):e136047. doi: 10.1172/jci.insight.136047. JCI Insight. 2020. PMID: 32554924 Free PMC article.
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