Gascoigne NRJ - Search Results

1

Colonization with ubiquitous protist Blastocystis ST1 ameliorates DSS-induced colitis and promotes beneficial microbiota and immune outcomes.

Deng L, Wojciech L, Png CW, Kioh YQD, Ng GC, Chan ECY, Zhang Y, Gascoigne NRJ, Tan KSW. Deng L, et al. Among authors: gascoigne nrj. NPJ Biofilms Microbiomes. 2023 Apr 25;9(1):22. doi: 10.1038/s41522-023-00389-1. NPJ Biofilms Microbiomes. 2023. PMID: 37185924 Free PMC article.

2

Lck bound to coreceptor is less active than free Lck.

Wei Q, Brzostek J, Sankaran S, Casas J, Hew LS, Yap J, Zhao X, Wojciech L, Gascoigne NRJ. Wei Q, et al. Among authors: gascoigne nrj. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15809-15817. doi: 10.1073/pnas.1913334117. Epub 2020 Jun 22. Proc Natl Acad Sci U S A. 2020. PMID: 32571924 Free PMC article.

3

Taming the Sentinels: Microbiome-Derived Metabolites and Polarization of T Cells.

Wojciech L, Tan KSW, Gascoigne NRJ. Wojciech L, et al. Among authors: gascoigne nrj. Int J Mol Sci. 2020 Oct 19;21(20):7740. doi: 10.3390/ijms21207740. Int J Mol Sci. 2020. PMID: 33086747 Free PMC article. Review.

4

New insights into the interactions between Blastocystis, the gut microbiota, and host immunity.

Deng L, Wojciech L, Gascoigne NRJ, Peng G, Tan KSW. Deng L, et al. Among authors: gascoigne nrj. PLoS Pathog. 2021 Feb 25;17(2):e1009253. doi: 10.1371/journal.ppat.1009253. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33630979 Free PMC article. Review.

5

DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death.

Low HB, Wong ZL, Wu B, Kong LR, Png CW, Cho YL, Li CW, Xiao F, Xin X, Yang H, Loo JM, Lee FYX, Tan IBH, DasGupta R, Shen HM, Schwarz H, Gascoigne NRJ, Goh BC, Xu X, Zhang Y. Low HB, et al. Among authors: gascoigne nrj. Nat Commun. 2021 Apr 16;12(1):2284. doi: 10.1038/s41467-021-22638-7. Nat Commun. 2021. PMID: 33863904 Free PMC article.

6

Expansion of an Unusual Virtual Memory CD8⁺ Subpopulation Bearing Vα3.2 TCR in Themis-Deficient Mice.

Prasad M, Wojciech L, Brzostek J, Hu J, Chua YL, Tung DWH, Yap J, Rybakin V, Gascoigne NRJ. Prasad M, et al. Among authors: gascoigne nrj. Front Immunol. 2021 Apr 7;12:644483. doi: 10.3389/fimmu.2021.644483. eCollection 2021. Front Immunol. 2021. PMID: 33897691 Free PMC article.

7

Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.

Zareie P, Szeto C, Farenc C, Gunasinghe SD, Kolawole EM, Nguyen A, Blyth C, Sng XYX, Li J, Jones CM, Fulcher AJ, Jacobs JR, Wei Q, Wojciech L, Petersen J, Gascoigne NRJ, Evavold BD, Gaus K, Gras S, Rossjohn J, La Gruta NL. Zareie P, et al. Among authors: gascoigne nrj. Science. 2021 Jun 4;372(6546):eabe9124. doi: 10.1126/science.abe9124. Science. 2021. PMID: 34083463

8

Themis controls T cell activation, effector functions, and metabolism of peripheral CD8⁺ T cells.

Gautam N, Wojciech L, Yap J, Chua YL, Ding EM, Sim DC, Tan AS, Ahl PJ, Prasad M, Tung DW, Connolly JE, Adriani G, Brzostek J, Gascoigne NR. Gautam N, et al. Life Sci Alliance. 2023 Sep 22;6(12):e202302156. doi: 10.26508/lsa.202302156. Print 2023 Dec. Life Sci Alliance. 2023. PMID: 37739454 Free PMC article.

9

A tryptophan metabolite made by a gut microbiome eukaryote induces pro-inflammatory T cells.

Wojciech L, Png CW, Koh EY, Kioh DYQ, Deng L, Wang Z, Wu LZ, Hamidinia M, Tung DW, Zhang W, Pettersson S, Chan ECY, Zhang Y, Tan KS, Gascoigne NR. Wojciech L, et al. EMBO J. 2023 Nov 2;42(21):e112963. doi: 10.15252/embj.2022112963. Epub 2023 Sep 25. EMBO J. 2023. PMID: 37743772 Free PMC article.

10

Themis suppresses the effector function of CD8⁺ T cells in acute viral infection.

Tang J, Jia X, Li J, Dong J, Wang J, Li W, Zhu Y, Hu Y, Hou B, Lin C, Cong Y, Ren T, Yan C, Yang H, Lai Q, Zheng H, Bao Y, Gautam N, Wang HR, Xu B, Chen XL, Li Q, Gascoigne NRJ, Fu G. Tang J, et al. Among authors: gascoigne nrj. Cell Mol Immunol. 2023 May;20(5):512-524. doi: 10.1038/s41423-023-00997-z. Epub 2023 Mar 28. Cell Mol Immunol. 2023. PMID: 36977779 Free PMC article.

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