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In vivo detection of amyloid β deposition using ¹⁹F magnetic resonance imaging with a ¹⁹F-containing curcumin derivative in a mouse model of Alzheimer's disease.
Yanagisawa D, Amatsubo T, Morikawa S, Taguchi H, Urushitani M, Shirai N, Hirao K, Shiino A, Inubushi T, Tooyama I. Yanagisawa D, et al. Among authors: taguchi h. Neuroscience. 2011 Jun 16;184:120-7. doi: 10.1016/j.neuroscience.2011.03.071. Epub 2011 Apr 12. Neuroscience. 2011. PMID: 21497641
Keto form of curcumin derivatives strongly binds to Aβ oligomers but not fibrils.
Yanagisawa D, Kato T, Taguchi H, Shirai N, Hirao K, Sogabe T, Tomiyama T, Gamo K, Hirahara Y, Kitada M, Tooyama I. Yanagisawa D, et al. Among authors: taguchi h. Biomaterials. 2021 Mar;270:120686. doi: 10.1016/j.biomaterials.2021.120686. Epub 2021 Jan 23. Biomaterials. 2021. PMID: 33540171 Free article.
Relationship between the tautomeric structures of curcumin derivatives and their Abeta-binding activities in the context of therapies for Alzheimer's disease.
Yanagisawa D, Shirai N, Amatsubo T, Taguchi H, Hirao K, Urushitani M, Morikawa S, Inubushi T, Kato M, Kato F, Morino K, Kimura H, Nakano I, Yoshida C, Okada T, Sano M, Wada Y, Wada KN, Yamamoto A, Tooyama I. Yanagisawa D, et al. Among authors: taguchi h. Biomaterials. 2010 May;31(14):4179-85. doi: 10.1016/j.biomaterials.2010.01.142. Epub 2010 Feb 23. Biomaterials. 2010. PMID: 20181392
1,385 results