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PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential.
Cristóbal I, Manso R, Rincón R, Caramés C, Senin C, Borrero A, Martínez-Useros J, Rodriguez M, Zazo S, Aguilera O, Madoz-Gúrpide J, Rojo F, García-Foncillas J. Cristóbal I, et al. Among authors: carames c. Mol Cancer Ther. 2014 Apr;13(4):938-47. doi: 10.1158/1535-7163.MCT-13-0150. Epub 2014 Jan 21. Mol Cancer Ther. 2014. PMID: 24448818
Hyperphosphorylation of PP2A in colorectal cancer and the potential therapeutic value showed by its forskolin-induced dephosphorylation and activation.
Cristóbal I, Rincón R, Manso R, Madoz-Gúrpide J, Caramés C, del Puerto-Nevado L, Rojo F, García-Foncillas J. Cristóbal I, et al. Among authors: carames c. Biochim Biophys Acta. 2014 Sep;1842(9):1823-9. doi: 10.1016/j.bbadis.2014.06.032. Epub 2014 Jul 2. Biochim Biophys Acta. 2014. PMID: 24997451 Free article.
MicroRNA-31 Emerges as a Predictive Biomarker of Pathological Response and Outcome in Locally Advanced Rectal Cancer.
Caramés C, Cristobal I, Moreno V, Marín JP, González-Alonso P, Torrejón B, Minguez P, Leon A, Martín JI, Hernández R, Pedregal M, Martín MJ, Cortés D, García-Olmo D, Fernández MJ, Rojo F, García-Foncillas J. Caramés C, et al. Int J Mol Sci. 2016 Jun 3;17(6):878. doi: 10.3390/ijms17060878. Int J Mol Sci. 2016. PMID: 27271609 Free PMC article.
Downregulation of microRNA-199b predicts unfavorable prognosis and emerges as a novel therapeutic target which contributes to PP2A inhibition in metastatic colorectal cancer.
Cristóbal I, Caramés C, Rincón R, Manso R, Madoz-Gúrpide J, Torrejón B, González-Alonso P, Rojo F, García-Foncillas J. Cristóbal I, et al. Among authors: carames c. Oncotarget. 2017 Jun 20;8(25):40169-40180. doi: 10.18632/oncotarget.11174. Oncotarget. 2017. PMID: 27517624 Free PMC article.
Functional and Clinical Impact of CircRNAs in Oral Cancer.
Cristóbal I, Caramés C, Rubio J, Sanz-Alvarez M, Luque M, Madoz-Gúrpide J, Rojo F, García-Foncillas J. Cristóbal I, et al. Among authors: carames c. Cancers (Basel). 2020 Apr 23;12(4):1041. doi: 10.3390/cancers12041041. Cancers (Basel). 2020. PMID: 32340253 Free PMC article. Review.
39 results