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Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel.
Sci Rep. 2023 May 10;13(1):7604. doi: 10.1038/s41598-023-34440-0.
Sci Rep. 2023.
PMID: 37165082
Free PMC article.
Functional restoration of a CFTR splicing mutation through RNA delivery of CRISPR adenine base editor.
Amistadi S, Maule G, Ciciani M, Ensinck MM, De Keersmaecker L, Ramalho AS, Guidone D, Buccirossi M, Galietta LJV, Carlon MS, Cereseto A.
Amistadi S, et al. Among authors: buccirossi m.
Mol Ther. 2023 Jun 7;31(6):1647-1660. doi: 10.1016/j.ymthe.2023.03.004. Epub 2023 Mar 9.
Mol Ther. 2023.
PMID: 36895161
Free article.
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Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening.
Genovese M, Guidone D, Buccirossi M, Borrelli A, Rodriguez-Gimeno A, Bertozzi F, Bandiera T, Galietta LJV.
Genovese M, et al. Among authors: buccirossi m.
PNAS Nexus. 2022 Dec 9;2(1):pgac288. doi: 10.1093/pnasnexus/pgac288. eCollection 2023 Jan.
PNAS Nexus. 2022.
PMID: 36712939
Free PMC article.
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Analysis of inhibitors of the anoctamin-1 chloride channel (transmembrane member 16A, TMEM16A) reveals indirect mechanisms involving alterations in calcium signalling.
Genovese M, Buccirossi M, Guidone D, De Cegli R, Sarnataro S, di Bernardo D, Galietta LJV.
Genovese M, et al. Among authors: buccirossi m.
Br J Pharmacol. 2023 Mar;180(6):775-785. doi: 10.1111/bph.15995. Epub 2022 Dec 18.
Br J Pharmacol. 2023.
PMID: 36444690
Free article.
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Airway surface hyperviscosity and defective mucociliary transport by IL-17/TNF-α are corrected by β-adrenergic stimulus.
Guidone D, Buccirossi M, Scudieri P, Genovese M, Sarnataro S, De Cegli R, Cresta F, Terlizzi V, Planelles G, Crambert G, Sermet I, Galietta LJ.
Guidone D, et al. Among authors: buccirossi m.
JCI Insight. 2022 Nov 22;7(22):e164944. doi: 10.1172/jci.insight.164944.
JCI Insight. 2022.
PMID: 36219481
Free PMC article.
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