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Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation.
Chhabra Y, Seiffert P, Gormal RS, Vullings M, Lee CMM, Wallis TP, Dehkhoda F, Indrakumar S, Jacobsen NL, Lindorff-Larsen K, Durisic N, Waters MJ, Meunier FA, Kragelund BB, Brooks AJ. Chhabra Y, et al. Among authors: brooks aj. Cell Rep. 2023 May 30;42(5):112490. doi: 10.1016/j.celrep.2023.112490. Epub 2023 May 9. Cell Rep. 2023. PMID: 37163374 Free article.
Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis.
Conway-Campbell BL, Wooh JW, Brooks AJ, Gordon D, Brown RJ, Lichanska AM, Chin HS, Barton CL, Boyle GM, Parsons PG, Jans DA, Waters MJ. Conway-Campbell BL, et al. Among authors: brooks aj. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13331-6. doi: 10.1073/pnas.0600181104. Epub 2007 Aug 9. Proc Natl Acad Sci U S A. 2007. PMID: 17690250 Free PMC article.
Growth hormone receptor; mechanism of action.
Brooks AJ, Wooh JW, Tunny KA, Waters MJ. Brooks AJ, et al. Int J Biochem Cell Biol. 2008;40(10):1984-9. doi: 10.1016/j.biocel.2007.07.008. Epub 2007 Jul 25. Int J Biochem Cell Biol. 2008. PMID: 17888716 Review.
Growth hormone and cell growth.
Waters MJ, Brooks AJ. Waters MJ, et al. Among authors: brooks aj. Endocr Dev. 2012;23:86-95. doi: 10.1159/000341761. Epub 2012 Nov 23. Endocr Dev. 2012. PMID: 23182823 Review.
Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling.
Fernández-Rojo MA, Gongora M, Fitzsimmons RL, Martel N, Martin SD, Nixon SJ, Brooks AJ, Ikonomopoulou MP, Martin S, Lo HP, Myers SA, Restall C, Ferguson C, Pilch PF, McGee SL, Anderson RL, Waters MJ, Hancock JF, Grimmond SM, Muscat GE, Parton RG. Fernández-Rojo MA, et al. Among authors: brooks aj. Cell Rep. 2013 Jul 25;4(2):238-47. doi: 10.1016/j.celrep.2013.06.017. Epub 2013 Jul 11. Cell Rep. 2013. PMID: 23850288 Free article.
Mechanism of activation of protein kinase JAK2 by the growth hormone receptor.
Brooks AJ, Dai W, O'Mara ML, Abankwa D, Chhabra Y, Pelekanos RA, Gardon O, Tunny KA, Blucher KM, Morton CJ, Parker MW, Sierecki E, Gambin Y, Gomez GA, Alexandrov K, Wilson IA, Doxastakis M, Mark AE, Waters MJ. Brooks AJ, et al. Science. 2014 May 16;344(6185):1249783. doi: 10.1126/science.1249783. Science. 2014. PMID: 24833397
208 results