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Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold.
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M. Qi C, et al. Among authors: goedert m. bioRxiv [Preprint]. 2023 Apr 28:2023.04.26.538417. doi: 10.1101/2023.04.26.538417. bioRxiv. 2023. PMID: 37162924 Free PMC article. Updated. Preprint.
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains.
Yang Y, Zhang W, Murzin AG, Schweighauser M, Huang M, Lövestam S, Peak-Chew SY, Saito T, Saido TC, Macdonald J, Lavenir I, Ghetti B, Graff C, Kumar A, Nordberg A, Goedert M, Scheres SHW. Yang Y, et al. Among authors: goedert m. Acta Neuropathol. 2023 Mar;145(3):325-333. doi: 10.1007/s00401-022-02533-1. Epub 2023 Jan 7. Acta Neuropathol. 2023. PMID: 36611124 Free PMC article.
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy.
Yang Y, Garringer HJ, Shi Y, Lövestam S, Peak-Chew S, Zhang X, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini MG, Ghetti B, Vidal R, Murzin AG, Scheres SHW, Goedert M. Yang Y, et al. Among authors: goedert m. Acta Neuropathol. 2023 May;145(5):561-572. doi: 10.1007/s00401-023-02550-8. Epub 2023 Feb 27. Acta Neuropathol. 2023. PMID: 36847833 Free PMC article.
Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Tarutani A, Lövestam S, Zhang X, Kotecha A, Robinson AC, Mann DMA, Saito Y, Murayama S, Tomita T, Goedert M, Scheres SHW, Hasegawa M. Tarutani A, et al. Among authors: goedert m. FEBS Open Bio. 2023 Aug;13(8):1394-1404. doi: 10.1002/2211-5463.13657. Epub 2023 Jul 7. FEBS Open Bio. 2023. PMID: 37337995 Free PMC article.
Mutation ∆K281 in MAPT causes Pick's disease.
Schweighauser M, Garringer HJ, Klingstedt T, Nilsson KPR, Masuda-Suzukake M, Murrell JR, Risacher SL, Vidal R, Scheres SHW, Goedert M, Ghetti B, Newell KL. Schweighauser M, et al. Among authors: goedert m. Acta Neuropathol. 2023 Aug;146(2):211-226. doi: 10.1007/s00401-023-02598-6. Epub 2023 Jun 23. Acta Neuropathol. 2023. PMID: 37351604 Free PMC article.
Tau and neurodegeneration.
Goedert M, Crowther RA, Scheres SHW, Spillantini MG. Goedert M, et al. Cytoskeleton (Hoboken). 2024 Jan;81(1):95-102. doi: 10.1002/cm.21812. Epub 2023 Dec 10. Cytoskeleton (Hoboken). 2024. PMID: 38073060 Free PMC article. Review.
399 results