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Complement contributes to antibody-mediated protection against repeated SHIV challenge.
Goldberg BS, Spencer DA, Pandey S, Ordonez T, Barnette P, Yu Y, Gao L, Dufloo J, Bruel T, Schwartz O, Ackerman ME, Hessell AJ. Goldberg BS, et al. Among authors: hessell aj. Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2221247120. doi: 10.1073/pnas.2221247120. Epub 2023 May 8. Proc Natl Acad Sci U S A. 2023. PMID: 37155897 Free PMC article.
Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody.
Burton DR, Hessell AJ, Keele BF, Klasse PJ, Ketas TA, Moldt B, Dunlop DC, Poignard P, Doyle LA, Cavacini L, Veazey RS, Moore JP. Burton DR, et al. Among authors: hessell aj. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11181-6. doi: 10.1073/pnas.1103012108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690411 Free PMC article.
Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.
Malherbe DC, Pissani F, Sather DN, Guo B, Pandey S, Sutton WF, Stuart AB, Robins H, Park B, Krebs SJ, Schuman JT, Kalams S, Hessell AJ, Haigwood NL. Malherbe DC, et al. Among authors: hessell aj. J Virol. 2014 Nov;88(22):12949-67. doi: 10.1128/JVI.01812-14. Epub 2014 Sep 10. J Virol. 2014. PMID: 25210191 Free PMC article.
Animal models in HIV-1 protection and therapy.
Hessell AJ, Haigwood NL. Hessell AJ, et al. Curr Opin HIV AIDS. 2015 May;10(3):170-6. doi: 10.1097/COH.0000000000000152. Curr Opin HIV AIDS. 2015. PMID: 25730345 Free PMC article. Review.
Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens.
Hessell AJ, Malherbe DC, Pissani F, McBurney S, Krebs SJ, Gomes M, Pandey S, Sutton WF, Burwitz BJ, Gray M, Robins H, Park BS, Sacha JB, LaBranche CC, Fuller DH, Montefiori DC, Stamatatos L, Sather DN, Haigwood NL. Hessell AJ, et al. J Immunol. 2016 Apr 1;196(7):3064-78. doi: 10.4049/jimmunol.1500527. Epub 2016 Mar 4. J Immunol. 2016. PMID: 26944928 Free PMC article.
Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques.
Hessell AJ, Jaworski JP, Epson E, Matsuda K, Pandey S, Kahl C, Reed J, Sutton WF, Hammond KB, Cheever TA, Barnette PT, Legasse AW, Planer S, Stanton JJ, Pegu A, Chen X, Wang K, Siess D, Burke D, Park BS, Axthelm MK, Lewis A, Hirsch VM, Graham BS, Mascola JR, Sacha JB, Haigwood NL. Hessell AJ, et al. Nat Med. 2016 Apr;22(4):362-8. doi: 10.1038/nm.4063. Epub 2016 Mar 21. Nat Med. 2016. PMID: 26998834 Free PMC article.
Reduced Cell-Associated DNA and Improved Viral Control in Macaques following Passive Transfer of a Single Anti-V2 Monoclonal Antibody and Repeated Simian/Human Immunodeficiency Virus Challenges.
Hessell AJ, Shapiro MB, Powell R, Malherbe DC, McBurney SP, Pandey S, Cheever T, Sutton WF, Kahl C, Park B, Zolla-Pazner S, Haigwood NL. Hessell AJ, et al. J Virol. 2018 May 14;92(11):e02198-17. doi: 10.1128/JVI.02198-17. Print 2018 Jun 1. J Virol. 2018. PMID: 29514914 Free PMC article.
68 results