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Epstein-Barr virus LMP1 protein promotes proliferation and inhibits differentiation of epithelial cells via activation of YAP and TAZ.
Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2219755120. doi: 10.1073/pnas.2219755120. Epub 2023 May 8.
Proc Natl Acad Sci U S A. 2023.
PMID: 37155846
Free PMC article.
Type 1 and Type 2 Epstein-Barr viruses induce proliferation, and inhibit differentiation, in infected telomerase-immortalized normal oral keratinocytes.
Singh DR, Nelson SE, Pawelski AS, Cantres-Velez JA, Kansra AS, Pauly NP, Bristol JA, Hayes M, Ohashi M, Casco A, Lee D, Fogarty SA, Lambert PF, Johannsen EC, Kenney SC.
Singh DR, et al. Among authors: fogarty sa.
PLoS Pathog. 2022 Oct 3;18(10):e1010868. doi: 10.1371/journal.ppat.1010868. eCollection 2022 Oct.
PLoS Pathog. 2022.
PMID: 36190982
Free PMC article.
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Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer.
Lee T, Christov PP, Shaw S, Tarr JC, Zhao B, Veerasamy N, Jeon KO, Mills JJ, Bian Z, Sensintaffar JL, Arnold AL, Fogarty SA, Perry E, Ramsey HE, Cook RS, Hollingshead M, Davis Millin M, Lee KM, Koss B, Budhraja A, Opferman JT, Kim K, Arteaga CL, Moore WJ, Olejniczak ET, Savona MR, Fesik SW.
Lee T, et al. Among authors: fogarty sa.
J Med Chem. 2019 Apr 25;62(8):3971-3988. doi: 10.1021/acs.jmedchem.8b01991. Epub 2019 Apr 16.
J Med Chem. 2019.
PMID: 30929420
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Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design.
Shaw S, Bian Z, Zhao B, Tarr JC, Veerasamy N, Jeon KO, Belmar J, Arnold AL, Fogarty SA, Perry E, Sensintaffar JL, Camper DV, Rossanese OW, Lee T, Olejniczak ET, Fesik SW.
Shaw S, et al. Among authors: fogarty sa.
J Med Chem. 2018 Mar 22;61(6):2410-2421. doi: 10.1021/acs.jmedchem.7b01155. Epub 2018 Mar 9.
J Med Chem. 2018.
PMID: 29323899
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