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Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation.
Chernyaeva L, Ratti G, Teirilä L, Fudo S, Rankka U, Pelkonen A, Korhonen P, Leskinen K, Keskitalo S, Salokas K, Gkolfinopoulou C, Crompton KE, Javanainen M, Happonen L, Varjosalo M, Malm T, Leinonen V, Chroni A, Saavalainen P, Meri S, Kajander T, Wollman AJ, Nissilä E, Haapasalo K. Chernyaeva L, et al. Among authors: keskitalo s. EMBO Rep. 2023 Jul 5;24(7):e56467. doi: 10.15252/embr.202256467. Epub 2023 May 8. EMBO Rep. 2023. PMID: 37155564 Free PMC article.
Functional analysis of FLT4 mutations associated with Nonne-Milroy lymphedema.
Verstraeten VL, Holnthoner W, van Steensel MA, Veraart JC, Bladergroen RS, Heckman CA, Keskitalo S, Frank J, Alitalo K, van Geel M, Steijlen PM. Verstraeten VL, et al. Among authors: keskitalo s. J Invest Dermatol. 2009 Feb;129(2):509-12. doi: 10.1038/jid.2008.246. Epub 2008 Aug 21. J Invest Dermatol. 2009. PMID: 18719607 Free article. No abstract available.
The protein interaction landscape of the human CMGC kinase group.
Varjosalo M, Keskitalo S, Van Drogen A, Nurkkala H, Vichalkovski A, Aebersold R, Gstaiger M. Varjosalo M, et al. Among authors: keskitalo s. Cell Rep. 2013 Apr 25;3(4):1306-20. doi: 10.1016/j.celrep.2013.03.027. Epub 2013 Apr 18. Cell Rep. 2013. PMID: 23602568 Free article.
Pool-seq driven proteogenomic database for Group G Streptococcus.
Weldatsadik RG, Datta N, Kolmeder C, Vuopio J, Kere J, Wilkman SV, Flatt JW, Vuento R, Haapasalo KJ, Keskitalo S, Varjosalo M, Jokiranta TS. Weldatsadik RG, et al. Among authors: keskitalo s. J Proteomics. 2019 Jun 15;201:84-92. doi: 10.1016/j.jprot.2019.04.015. Epub 2019 Apr 20. J Proteomics. 2019. PMID: 31015036
Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy.
Göös H, Fogarty CL, Sahu B, Plagnol V, Rajamäki K, Nurmi K, Liu X, Einarsdottir E, Jouppila A, Pettersson T, Vihinen H, Krjutskov K, Saavalainen P, Järvinen A, Muurinen M, Greco D, Scala G, Curtis J, Nordström D, Flaumenhaft R, Vaarala O, Kovanen PE, Keskitalo S, Ranki A, Kere J, Lehto M, Notarangelo LD, Nejentsev S, Eklund KK, Varjosalo M, Taipale J, Seppänen MRJ. Göös H, et al. Among authors: keskitalo s. J Allergy Clin Immunol. 2019 Nov;144(5):1364-1376. doi: 10.1016/j.jaci.2019.06.003. Epub 2019 Jun 13. J Allergy Clin Immunol. 2019. PMID: 31201888 Free PMC article.
SARS-CoV-2-host proteome interactions for antiviral drug discovery.
Liu X, Huuskonen S, Laitinen T, Redchuk T, Bogacheva M, Salokas K, Pöhner I, Öhman T, Tonduru AK, Hassinen A, Gawriyski L, Keskitalo S, Vartiainen MK, Pietiäinen V, Poso A, Varjosalo M. Liu X, et al. Among authors: keskitalo s. Mol Syst Biol. 2021 Nov;17(11):e10396. doi: 10.15252/msb.202110396. Mol Syst Biol. 2021. PMID: 34709727 Free PMC article.
Analyzing Protein Interactions by MAC-Tag Approaches.
Liu X, Salokas K, Keskitalo S, Martínez-Botía P, Varjosalo M. Liu X, et al. Among authors: keskitalo s. Methods Mol Biol. 2023;2690:281-297. doi: 10.1007/978-1-0716-3327-4_24. Methods Mol Biol. 2023. PMID: 37450155
45 results