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Propensities of Fatty Acid-Modified ASOs: Self-Assembly vs Albumin Binding.
Kusznir EA, Hau JC, Portmann M, Reinhart AG, Falivene F, Bastien J, Worm J, Ross A, Lauer M, Ringler P, Sladojevich F, Huber S, Bleicher K, Keller M. Kusznir EA, et al. Among authors: bleicher k. Bioconjug Chem. 2023 May 17;34(5):866-879. doi: 10.1021/acs.bioconjchem.3c00085. Epub 2023 May 5. Bioconjug Chem. 2023. PMID: 37145959
Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in male rats.
Janz P, Knoflach F, Bleicher K, Belli S, Biemans B, Schnider P, Ebeling M, Grundschober C, Benekareddy M. Janz P, et al. Among authors: bleicher k. Front Cell Neurosci. 2023 Dec 7;17:1286552. doi: 10.3389/fncel.2023.1286552. eCollection 2023. Front Cell Neurosci. 2023. PMID: 38145283 Free PMC article.
A novel antibiotic class targeting the lipopolysaccharide transporter.
Zampaloni C, Mattei P, Bleicher K, Winther L, Thäte C, Bucher C, Adam JM, Alanine A, Amrein KE, Baidin V, Bieniossek C, Bissantz C, Boess F, Cantrill C, Clairfeuille T, Dey F, Di Giorgio P, du Castel P, Dylus D, Dzygiel P, Felici A, García-Alcalde F, Haldimann A, Leipner M, Leyn S, Louvel S, Misson P, Osterman A, Pahil K, Rigo S, Schäublin A, Scharf S, Schmitz P, Stoll T, Trauner A, Zoffmann S, Kahne D, Young JAT, Lobritz MA, Bradley KA. Zampaloni C, et al. Among authors: bleicher k. Nature. 2024 Jan;625(7995):566-571. doi: 10.1038/s41586-023-06873-0. Epub 2024 Jan 3. Nature. 2024. PMID: 38172634 Free PMC article.
Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers.
Duschmalé J, Schäublin A, Funder E, Schmidt S, Kiełpiński ŁJ, Nymark H, Jensen K, Koch T, Duschmalé M, Koller E, Møller MR, Schadt S, Husser C, Brink A, Sewing S, Minz T, Wengel J, Bleicher K, Li M. Duschmalé J, et al. Among authors: bleicher k. Mol Ther Nucleic Acids. 2022 Jun 22;29:176-188. doi: 10.1016/j.omtn.2022.06.010. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 35860384 Free PMC article.
Cohort Profile Update: The 45 and Up Study.
Bleicher K, Summerhayes R, Baynes S, Swarbrick M, Navin Cristina T, Luc H, Dawson G, Cowle A, Dolja-Gore X, McNamara M. Bleicher K, et al. Int J Epidemiol. 2023 Feb 8;52(1):e92-e101. doi: 10.1093/ije/dyac104. Int J Epidemiol. 2023. PMID: 35604374 Free PMC article. No abstract available.
Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.
Kang W, Podtelezhnikov AA, Tanis KQ, Pacchione S, Su M, Bleicher KB, Wang Z, Laws GM, Griffiths TG, Kuhls MC, Chen Q, Knemeyer I, Marsh DJ, Mitra K, Lebron J, Sistare FD. Kang W, et al. Among authors: bleicher kb. Toxicol Sci. 2020 Sep 1;177(1):121-139. doi: 10.1093/toxsci/kfaa094. Toxicol Sci. 2020. PMID: 32559289
40 results