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Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation.
Hill SE, Beaulieu-Abdelahad D, Lemus A, Webster JM, Ospina SR, Darling AL, Martin MD, Patel S, Bridenstine L, Swonger R, Paul S, Blackburn R, Calcul L, Dickey CA, Leahy JW, Blair LJ. Hill SE, et al. Among authors: darling al. ACS Chem Biol. 2023 May 19;18(5):1124-1135. doi: 10.1021/acschembio.2c00919. Epub 2023 May 5. ACS Chem Biol. 2023. PMID: 37144894 Free PMC article.
Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.
Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J 3rd, Dickey CA, Blair LJ. Sabbagh JJ, et al. Among authors: darling al. ACS Chem Biol. 2018 Aug 17;13(8):2288-2299. doi: 10.1021/acschembio.8b00454. Epub 2018 Jun 19. ACS Chem Biol. 2018. PMID: 29893552 Free PMC article.
Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels.
Webster JM, Darling AL, Sanders TA, Blazier DM, Vidal-Aguiar Y, Beaulieu-Abdelahad D, Plemmons DG, Hill SE, Uversky VN, Bickford PC, Dickey CA, Blair LJ. Webster JM, et al. Among authors: darling al. Int J Mol Sci. 2020 Jul 30;21(15):5442. doi: 10.3390/ijms21155442. Int J Mol Sci. 2020. PMID: 32751642 Free PMC article.
Cellular factors modulating the mechanism of tau protein aggregation.
Fontaine SN, Sabbagh JJ, Baker J, Martinez-Licha CR, Darling A, Dickey CA. Fontaine SN, et al. Cell Mol Life Sci. 2015 May;72(10):1863-79. doi: 10.1007/s00018-015-1839-9. Epub 2015 Feb 11. Cell Mol Life Sci. 2015. PMID: 25666877 Free PMC article. Review.
Human cyclophilin 40 unravels neurotoxic amyloids.
Baker JD, Shelton LB, Zheng D, Favretto F, Nordhues BA, Darling A, Sullivan LE, Sun Z, Solanki PK, Martin MD, Suntharalingam A, Sabbagh JJ, Becker S, Mandelkow E, Uversky VN, Zweckstetter M, Dickey CA, Koren J 3rd, Blair LJ. Baker JD, et al. PLoS Biol. 2017 Jun 27;15(6):e2001336. doi: 10.1371/journal.pbio.2001336. eCollection 2017 Jun. PLoS Biol. 2017. PMID: 28654636 Free PMC article.
57 results