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Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states.
Al-Dalahmah O, Argenziano MG, Kannan A, Mahajan A, Furnari J, Paryani F, Boyett D, Save A, Humala N, Khan F, Li J, Lu H, Sun Y, Tuddenham JF, Goldberg AR, Dovas A, Banu MA, Sudhakar T, Bush E, Lassman AB, McKhann GM, Gill BJA, Youngerman B, Sisti MB, Bruce JN, Sims PA, Menon V, Canoll P. Al-Dalahmah O, et al. Among authors: mckhann gm. Nat Commun. 2023 May 4;14(1):2586. doi: 10.1038/s41467-023-38186-1. Nat Commun. 2023. PMID: 37142563 Free PMC article.
Long-term outcomes of mesial temporal laser interstitial thermal therapy for drug-resistant epilepsy and subsequent surgery for seizure recurrence: a multi-centre cohort study.
Youngerman BE, Banu MA, Khan F, McKhann GM, Schevon CA, Jagid JR, Cajigas I, Theodotou CB, Ko A, Buckley R, Ojemann JG, Miller JW, Laxton AW, Couture DE, Popli GS, Buch VP, Halpern CH, Le S, Sharan AD, Sperling MR, Mehta AD, Englot DJ, Neimat JS, Konrad PE, Sheth SA, Neal EG, Vale FL, Holloway KL, Air EL, Schwalb JM, D'Haese PF, Wu C. Youngerman BE, et al. Among authors: mckhann gm. J Neurol Neurosurg Psychiatry. 2023 Nov;94(11):879-886. doi: 10.1136/jnnp-2022-330979. Epub 2023 Jun 19. J Neurol Neurosurg Psychiatry. 2023. PMID: 37336643
Seizure onset patterns predict outcome after stereo-electroencephalography-guided laser amygdalohippocampotomy.
Michalak AJ, Greenblatt A, Wu S, Tobochnik S, Dave H, Raghupathi R, Esengul YT, Guerra A, Tao JX, Issa NP, Cosgrove GR, Lega B, Warnke P, Chen HI, Lucas T, Sheth SA, Banks GP, Kwon CS, Feldstein N, Youngerman B, McKhann G, Davis KA, Schevon CA. Michalak AJ, et al. Epilepsia. 2023 Jun;64(6):1568-1581. doi: 10.1111/epi.17602. Epub 2023 Apr 24. Epilepsia. 2023. PMID: 37013668 Free PMC article.
Spatiotemporal spike-centered averaging reveals symmetry of temporal and spatial components of the spike-LFP relationship during human focal seizures.
Lee S, Deshpande SS, Merricks EM, Schlafly E, Goodman R, McKhann GM, Eskandar EN, Madsen JR, Cash SS, van Putten MJAM, Schevon CA, van Drongelen W. Lee S, et al. Among authors: mckhann gm. Commun Biol. 2023 Mar 25;6(1):317. doi: 10.1038/s42003-023-04696-3. Commun Biol. 2023. PMID: 36966217 Free PMC article.
CHD2 Regulates Neuron-glioma Interactions in Pediatric Glioma.
Zhang X, Duan S, Apostolou PE, Wu X, Watanabe J, Gallitto M, Barron T, Taylor KR, Woo PJ, Hua X, Zhou H, Wei HJ, McQuillan N, Kang KD, Friedman GK, Canoll PD, Chang K, Wu CC, Hashizume R, Vakoc CR, Monje M, McKhann GM, Gogos JA, Zhang Z. Zhang X, et al. Among authors: mckhann gm. Cancer Discov. 2024 May 20. doi: 10.1158/2159-8290.CD-23-0012. Online ahead of print. Cancer Discov. 2024. PMID: 38767413
Aberrant fast spiking interneuronal activity precedes seizure transitions in humans.
Merricks EM, Deshpande SS, Agopyan-Miu AH, Smith EH, Schlafly ED, McKhann GM, Goodman RR, Sheth SA, Greger B, House PA, Eskandar EN, Madsen JR, Cash SS, Trevelyan AJ, van Drongelen W, Schevon CA. Merricks EM, et al. Among authors: mckhann gm. medRxiv [Preprint]. 2024 Jan 26:2024.01.26.24301821. doi: 10.1101/2024.01.26.24301821. medRxiv. 2024. PMID: 38343792 Free PMC article. Preprint.
Awake intraoperative mapping for the prevention of amusia.
Wang L, Higgins D, Delgardo M, Chang C, Hamberger MJ, McKhann GM. Wang L, et al. Among authors: mckhann gm. Neurosurg Focus. 2024 Feb;56(2):E8. doi: 10.3171/2023.11.FOCUS23600. Neurosurg Focus. 2024. PMID: 38301242
Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition.
Goldberg AR, Dovas A, Torres D, Sharma SD, Mela A, Merricks EM, Olabarria M, Shokooh LA, Zhao HT, Kotidis C, Calvaresi P, Viswanathan A, Banu MA, Razavilar A, Sudhakar TD, Saxena A, Chokran C, Humala N, Mahajan A, Xu W, Metz JB, Chen C, Bushong EA, Boassa D, Ellisman MH, Hillman EMC, McKhann GM 2nd, Gill BJA, Rosenfeld SS, Schevon CA, Bruce JN, Sims PA, Peterka DS, Canoll P. Goldberg AR, et al. Among authors: mckhann gm 2nd. bioRxiv [Preprint]. 2024 Jan 21:2024.01.10.575092. doi: 10.1101/2024.01.10.575092. bioRxiv. 2024. PMID: 38293120 Free PMC article. Preprint.
418 results