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Synthesis of entecavir and its novel class of analogs.
Rawal RK, Singh US, Gadthula S, Chu CK. Rawal RK, et al. Among authors: singh us. Curr Protoc Nucleic Acid Chem. 2011 Dec;Chapter 14:Unit 14.7.1-17. doi: 10.1002/0471142700.nc1407s47. Curr Protoc Nucleic Acid Chem. 2011. PMID: 22147419
2'-Fluoro-6'-methylene-carbocyclic adenosine phosphoramidate (FMCAP) prodrug: in vitro anti-HBV activity against the lamivudine-entecavir resistant triple mutant and its mechanism of action.
Rawal RK, Singh US, Chavre SN, Wang J, Sugiyama M, Hung W, Govindarajan R, Korba B, Tanaka Y, Chu CK. Rawal RK, et al. Among authors: singh us. Bioorg Med Chem Lett. 2013 Jan 15;23(2):503-6. doi: 10.1016/j.bmcl.2012.11.027. Epub 2012 Nov 24. Bioorg Med Chem Lett. 2013. PMID: 23237841
β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.
De C, Liu D, Zheng B, Singh US, Chavre S, White C, Arnold RD, Hagen FK, Chu CK, Moffat JF. De C, et al. Among authors: singh us. Antiviral Res. 2014 Oct;110:10-9. doi: 10.1016/j.antiviral.2014.07.007. Epub 2014 Jul 19. Antiviral Res. 2014. PMID: 25051026 Free PMC article.
180 results