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An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Indeglia A, Leung JC, Miller SA, Leu JI, Dougherty JF, Clarke NL, Kirven NA, Shao C, Ke L, Lovell S, Barnoud T, Lu DY, Lin C, Kannan T, Battaile KP, Yang THL, Batista Oliva I, Claiborne DT, Vogel P, Liu L, Liu Q, Nefedova Y, Cassel J, Auslander N, Kossenkov AV, Karanicolas J, Murphy ME. Indeglia A, et al. Among authors: karanicolas j. Cancer Discov. 2023 Jul 7;13(7):1696-1719. doi: 10.1158/2159-8290.CD-22-1315. Cancer Discov. 2023. PMID: 37140445 Free PMC article.
Rationalizing PROTAC-Mediated Ternary Complex Formation Using Rosetta.
Bai N, Miller SA, Andrianov GV, Yates M, Kirubakaran P, Karanicolas J. Bai N, et al. Among authors: karanicolas j. J Chem Inf Model. 2021 Mar 22;61(3):1368-1382. doi: 10.1021/acs.jcim.0c01451. Epub 2021 Feb 24. J Chem Inf Model. 2021. PMID: 33625214 Free PMC article.
The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors.
Topchu I, Pangeni RP, Bychkov I, Miller SA, Izumchenko E, Yu J, Golemis E, Karanicolas J, Boumber Y. Topchu I, et al. Among authors: karanicolas j. Cell Mol Life Sci. 2022 May 9;79(6):285. doi: 10.1007/s00018-022-04321-2. Cell Mol Life Sci. 2022. PMID: 35532818 Free PMC article. Review.
Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry.
Bai N, Adeshina Y, Bychkov I, Xia Y, Gowthaman R, Miller SA, Gupta AK, Johnson DK, Lan L, Golemis EA, Makhov PB, Xu L, Pillai MM, Boumber Y, Karanicolas J. Bai N, et al. Among authors: karanicolas j. Res Sq [Preprint]. 2023 Jan 10:rs.3.rs-2395172. doi: 10.21203/rs.3.rs-2395172/v1. Res Sq. 2023. PMID: 36711552 Free PMC article. Preprint.
Full and Partial Agonism of a Designed Enzyme Switch.
Budiardjo SJ, Licknack TJ, Cory MB, Kapros D, Roy A, Lovell S, Douglas J, Karanicolas J. Budiardjo SJ, et al. Among authors: karanicolas j. ACS Synth Biol. 2016 Dec 16;5(12):1475-1484. doi: 10.1021/acssynbio.6b00097. Epub 2016 Jul 22. ACS Synth Biol. 2016. PMID: 27389009 Free PMC article.
74 results