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Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort.
Shaw DE, Sousa AR, Fowler SJ, Fleming LJ, Roberts G, Corfield J, Pandis I, Bansal AT, Bel EH, Auffray C, Compton CH, Bisgaard H, Bucchioni E, Caruso M, Chanez P, Dahlén B, Dahlen SE, Dyson K, Frey U, Geiser T, Gerhardsson de Verdier M, Gibeon D, Guo YK, Hashimoto S, Hedlin G, Jeyasingham E, Hekking PP, Higenbottam T, Horváth I, Knox AJ, Krug N, Erpenbeck VJ, Larsson LX, Lazarinis N, Matthews JG, Middelveld R, Montuschi P, Musial J, Myles D, Pahus L, Sandström T, Seibold W, Singer F, Strandberg K, Vestbo J, Vissing N, von Garnier C, Adcock IM, Wagers S, Rowe A, Howarth P, Wagener AH, Djukanovic R, Sterk PJ, Chung KF; U-BIOPRED Study Group. Shaw DE, et al. Among authors: sousa ar. Eur Respir J. 2015 Nov;46(5):1308-21. doi: 10.1183/13993003.00779-2015. Epub 2015 Sep 10. Eur Respir J. 2015. PMID: 26357963 Free article.
Assessment of the efficacy and safety of fluticasone propionate and salmeterol delivered as a combination dry powder via a capsule-based inhaler and a multi-dose inhaler in patients with asthma.
Chan R, Sousa AR, Mallett S, Hynds P, Homayoun-Valiani F, Tabberer M, Mehta R. Chan R, et al. Among authors: sousa ar. Pulm Pharmacol Ther. 2016 Dec;41:19-24. doi: 10.1016/j.pupt.2016.09.002. Epub 2016 Sep 4. Pulm Pharmacol Ther. 2016. PMID: 27599598 Clinical Trial.
Assessment of the efficacy and safety of fluticasone propionate and salmeterol delivered as a combination dry powder via a capsule-based inhaler versus a multi-dose inhaler in patients with chronic obstructive pulmonary disease.
Chan R, Sousa AR, Hynds P, Homayoun-Valiani F, Edwards D, Tabberer M. Chan R, et al. Among authors: sousa ar. Pulm Pharmacol Ther. 2017 Apr;43:12-19. doi: 10.1016/j.pupt.2017.01.009. Epub 2017 Jan 21. Pulm Pharmacol Ther. 2017. PMID: 28115223 Clinical Trial.
Pathway discovery using transcriptomic profiles in adult-onset severe asthma.
Hekking PP, Loza MJ, Pavlidis S, de Meulder B, Lefaudeux D, Baribaud F, Auffray C, Wagener AH, Brinkman P Ir, Lutter R Ir, Bansal AT, Sousa AR, Bates SA, Pandis Y, Fleming LJ, Shaw DE, Fowler SJ, Guo Y, Meiser A, Sun K, Corfield J, Howarth PH, Bel EH, Adcock IM, Chung KF, Djukanovic R, Sterk PJ; U-BIOPRED Study Group. Hekking PP, et al. Among authors: sousa ar. J Allergy Clin Immunol. 2018 Apr;141(4):1280-1290. doi: 10.1016/j.jaci.2017.06.037. Epub 2017 Jul 26. J Allergy Clin Immunol. 2018. PMID: 28756296 Free article.
Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma.
Hekking PP, Loza MJ, Pavlidis S, De Meulder B, Lefaudeux D, Baribaud F, Auffray C, Wagener AH, Brinkman P, Lutter R, Bansal AT, Sousa AR, Bates SA, Pandis I, Fleming LJ, Shaw DE, Fowler SJ, Guo Y, Meiser A, Sun K, Corfield J, Howarth P, Bel EH, Adcock IM, Chung KF, Djukanovic R, Sterk PJ; U-BIOPRED Study Group. Hekking PP, et al. Among authors: sousa ar. Eur Respir J. 2017 Sep 27;50(3):1602298. doi: 10.1183/13993003.02298-2016. Print 2017 Sep. Eur Respir J. 2017. PMID: 28954779 Free article.
"T2-high" in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin.
Pavlidis S, Takahashi K, Ng Kee Kwong F, Xie J, Hoda U, Sun K, Elyasigomari V, Agapow P, Loza M, Baribaud F, Chanez P, Fowler SJ, Shaw DE, Fleming LJ, Howarth PH, Sousa AR, Corfield J, Auffray C, De Meulder B, Knowles R, Sterk PJ, Guo Y, Adcock IM, Djukanovic R, Fan Chung K; on behalf of the U-BIOPRED Study Group. Pavlidis S, et al. Among authors: sousa ar. Eur Respir J. 2019 Jan 3;53(1):1800938. doi: 10.1183/13993003.00938-2018. Print 2019 Jan. Eur Respir J. 2019. PMID: 30578390 Free article.
Instability of sputum molecular phenotypes in U-BIOPRED severe asthma.
Kermani NZ, Pavlidis S, Xie J, Sun K, Loza M, Baribaud F, Fowler SJ, Shaw DE, Fleming LJ, Howarth PH, Sousa AR, Corfield J, Auffray C, De Meulder B, Sterk PJ, Guo Y, Uddin M, Djukanovic R, Adcock IM, Chung KF; U-BIOPRED study group. Kermani NZ, et al. Among authors: sousa ar. Eur Respir J. 2021 Feb 4;57(2):2001836. doi: 10.1183/13993003.01836-2020. Print 2021 Feb. Eur Respir J. 2021. PMID: 33008937 Free PMC article.
Airway Elastin is increased in severe asthma and relates to proximal wall area: histological and computed tomography findings from the U-BIOPRED severe asthma study.
Wilson SJ, Ward JA, Pickett HM, Baldi S, Sousa AR, Sterk PJ, Chung KF, Djukanovic R, Dahlen B, Billing B, Shaw D, Krug N, Sandstrӧm T, Brightling C, Howarth PH; U-BIOPRED consortium. Wilson SJ, et al. Among authors: sousa ar. Clin Exp Allergy. 2021 Feb;51(2):296-304. doi: 10.1111/cea.13813. Epub 2021 Jan 10. Clin Exp Allergy. 2021. PMID: 33342006
225 results