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Candida parapsilosis isolates carrying mutations outside FKS1 hotspot regions confer high echinocandin tolerance and facilitate the development of echinocandin resistance.
Daneshnia F, Arastehfar A, Lombardi L, Binder U, Scheler J, Vahedi Shahandashti R, Hagen F, Lass-Flörl C, Mansour MK, Butler G, Perlin DS. Daneshnia F, et al. Among authors: perlin ds. Int J Antimicrob Agents. 2023 Jul;62(1):106831. doi: 10.1016/j.ijantimicag.2023.106831. Epub 2023 Apr 28. Int J Antimicrob Agents. 2023. PMID: 37121442 Free article.
Worldwide emergence of fluconazole-resistant Candida parapsilosis: current framework and future research roadmap.
Daneshnia F, de Almeida Júnior JN, Ilkit M, Lombardi L, Perry AM, Gao M, Nobile CJ, Egger M, Perlin DS, Zhai B, Hohl TM, Gabaldón T, Colombo AL, Hoenigl M, Arastehfar A. Daneshnia F, et al. Among authors: perlin ds. Lancet Microbe. 2023 Jun;4(6):e470-e480. doi: 10.1016/S2666-5247(23)00067-8. Epub 2023 Apr 27. Lancet Microbe. 2023. PMID: 37121240 Free PMC article. Review.
Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness.
Arastehfar A, Daneshnia F, Hovhannisyan H, Fuentes D, Cabrera N, Quintin C, Ilkit M, Ünal N, Hilmioğlu-Polat S, Jabeen K, Zaka S, Desai JV, Lass-Flörl C, Shor E, Gabaldon T, Perlin DS. Arastehfar A, et al. Among authors: perlin ds. bioRxiv [Preprint]. 2023 Jun 16:2023.06.15.545195. doi: 10.1101/2023.06.15.545195. bioRxiv. 2023. PMID: 37398397 Free PMC article. Updated. Preprint.
Determinants of fluconazole resistance and the efficacy of fluconazole and milbemycin oxim combination against Candida parapsilosis clinical isolates from Brazil and Turkey.
Daneshnia F, Hilmioğlu Polat S, Ilkit M, Shor E, de Almeida Júnior JN, Favarello LM, Colombo AL, Arastehfar A, Perlin DS. Daneshnia F, et al. Among authors: perlin ds. Front Fungal Biol. 2022 Jul 28;3:906681. doi: 10.3389/ffunb.2022.906681. eCollection 2022. Front Fungal Biol. 2022. PMID: 37746198 Free PMC article.
Decreased echinocandin susceptibility in Candida parapsilosis causing candidemia and emergence of a pan-echinocandin resistant case in China.
Ning Y, Xiao M, Perlin DS, Zhao Y, Lu M, Li Y, Luo Z, Dai R, Li S, Xu J, Liu L, He H, Liu Y, Li F, Guo Y, Chen Z, Xu Y, Sun T, Zhang L. Ning Y, et al. Among authors: perlin ds. Emerg Microbes Infect. 2023 Dec;12(1):2153086. doi: 10.1080/22221751.2022.2153086. Emerg Microbes Infect. 2023. PMID: 36440795 Free PMC article.
Fungicide-tolerant persister formation during cryptococcal pulmonary infection.
Ke W, Xie Y, Chen Y, Ding H, Ye L, Qiu H, Li H, Zhang L, Chen L, Tian X, Shen Z, Song Z, Fan X, Zong JF, Guo Z, Ma X, Xiao M, Liao G, Liu CH, Yin WB, Dong Z, Yang F, Jiang YY, Perlin DS, Chen Y, Fu YV, Wang L. Ke W, et al. Among authors: perlin ds. Cell Host Microbe. 2024 Feb 14;32(2):276-289.e7. doi: 10.1016/j.chom.2023.12.012. Epub 2024 Jan 11. Cell Host Microbe. 2024. PMID: 38215741
336 results