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Safety, tolerability, pharmacokinetics, and efficacy of kukoamine B in patients with sepsis: A randomized phase IIa trial.
Hu XY, Zhang W, Wang D, Sun Y, Hu Z, Zang B, Feng Y, Wang H, Zhou J, Zhao Q, Liu H, Wang T, Jiang W, Wang CY, Jin C, Dong K, Chen S, Yao X, Hu P, Du B; China Critical Care Clinical Trials Group (CCCCTG). Hu XY, et al. Among authors: wang h, wang cy, wang d, wang t. J Crit Care. 2023 Aug;76:154294. doi: 10.1016/j.jcrc.2023.154294. Epub 2023 Apr 26. J Crit Care. 2023. PMID: 37116228 Clinical Trial.
Safety, Tolerability, and Pharmacokinetics of Kukoamine B in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Phase I Study.
Zhao Q, Liu H, Wang Z, Wang T, Cui C, Wang H, Li L, Zhong W, Jiang J, Dong K, Chen S, Jin C, Hu P. Zhao Q, et al. Among authors: wang h, wang z, wang t. Adv Ther. 2023 Jul;40(7):3186-3198. doi: 10.1007/s12325-023-02521-1. Epub 2023 May 26. Adv Ther. 2023. PMID: 37233875 Free PMC article. Clinical Trial.
First-in-Human Safety, Tolerability, and Pharmacokinetics of Single-Dose Kukoamine B Mesylate in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Phase I Study.
Liu H, Zhao Q, Yuan Y, Wang Z, Wang T, Tian W, Zhong W, Jiang J, Chen S, Kong K, Jin C, Hu P. Liu H, et al. Among authors: wang z, wang t. Infect Dis Ther. 2024 Feb;13(2):361-371. doi: 10.1007/s40121-024-00921-6. Epub 2024 Jan 30. Infect Dis Ther. 2024. PMID: 38291280 Free PMC article.
Pharmacokinetics and Comparative Bioavailability of Test or Reference Capecitabine and Discrepant Pharmacokinetics Among Various Tumors in Chinese Solid Cancer Patients.
Li X, Cui D, Xiong J, Dang Q, Wen Q, Yan M, Li H, Jiang X, Lin C, Xie X, Wang T, Xiang L, Wang Y, Zheng L. Li X, et al. Among authors: wang y, wang t. Clin Pharmacol Drug Dev. 2023 Mar;12(3):324-332. doi: 10.1002/cpdd.1202. Epub 2023 Jan 15. Clin Pharmacol Drug Dev. 2023. PMID: 36642942
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