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In vitro and in vivo experimental models for drug screening and development for Chagas disease.
Romanha AJ, Castro SL, Soeiro Mde N, Lannes-Vieira J, Ribeiro I, Talvani A, Bourdin B, Blum B, Olivieri B, Zani C, Spadafora C, Chiari E, Chatelain E, Chaves G, Calzada JE, Bustamante JM, Freitas-Junior LH, Romero LI, Bahia MT, Lotrowska M, Soares M, Andrade SG, Armstrong T, Degrave W, Andrade Zde A. Romanha AJ, et al. Mem Inst Oswaldo Cruz. 2010 Mar;105(2):233-8. doi: 10.1590/s0074-02762010000200022. Mem Inst Oswaldo Cruz. 2010. PMID: 20428688 Free article.
Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment.
Batista Dda G, Batista MM, de Oliveira GM, do Amaral PB, Lannes-Vieira J, Britto CC, Junqueira A, Lima MM, Romanha AJ, Sales Junior PA, Stephens CE, Boykin DW, Soeiro Mde N. Batista Dda G, et al. Antimicrob Agents Chemother. 2010 Jul;54(7):2940-52. doi: 10.1128/AAC.01617-09. Epub 2010 May 10. Antimicrob Agents Chemother. 2010. PMID: 20457822 Free PMC article.
Identification of Pyrazolo[3,4-e][1,4]thiazepin based CYP51 inhibitors as potential Chagas disease therapeutic alternative: In vitro and in vivo evaluation, binding mode prediction and SAR exploration.
Ferreira de Almeida Fiuza L, Peres RB, Simões-Silva MR, da Silva PB, Batista DDGJ, da Silva CF, Nefertiti Silva da Gama A, Krishna Reddy TR, Soeiro MNC. Ferreira de Almeida Fiuza L, et al. Among authors: soeiro mnc. Eur J Med Chem. 2018 Apr 10;149:257-268. doi: 10.1016/j.ejmech.2018.02.020. Epub 2018 Feb 23. Eur J Med Chem. 2018. PMID: 29501946 Free article.
Imidazole Derivatives as Promising Agents for the Treatment of Chagas Disease.
de Araújo JS, García-Rubia A, Sebastián-Pérez V, Kalejaiye TD, Bernardino da Silva P, Fonseca-Berzal CR, Maes L, De Koning HP, Soeiro MNC, Gil C. de Araújo JS, et al. Among authors: soeiro mnc. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02156-18. doi: 10.1128/AAC.02156-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30670432 Free PMC article.
77 results