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Functional development of the T cell receptor for antigen.
Ebert PJ, Li QJ, Huppa JB, Davis MM. Ebert PJ, et al. Among authors: huppa jb. Prog Mol Biol Transl Sci. 2010;92:65-100. doi: 10.1016/S1877-1173(10)92004-8. Prog Mol Biol Transl Sci. 2010. PMID: 20800817 Free PMC article.
RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.
Salzer E, Cagdas D, Hons M, Mace EM, Garncarz W, Petronczki ÖY, Platzer R, Pfajfer L, Bilic I, Ban SA, Willmann KL, Mukherjee M, Supper V, Hsu HT, Banerjee PP, Sinha P, McClanahan F, Zlabinger GJ, Pickl WF, Gribben JG, Stockinger H, Bennett KL, Huppa JB, Dupré L, Sanal Ö, Jäger U, Sixt M, Tezcan I, Orange JS, Boztug K. Salzer E, et al. Among authors: huppa jb. Nat Immunol. 2016 Dec;17(12):1352-1360. doi: 10.1038/ni.3575. Epub 2016 Oct 24. Nat Immunol. 2016. PMID: 27776107 Free PMC article.
Monomeric TCRs drive T cell antigen recognition.
Brameshuber M, Kellner F, Rossboth BK, Ta H, Alge K, Sevcsik E, Göhring J, Axmann M, Baumgart F, Gascoigne NRJ, Davis SJ, Stockinger H, Schütz GJ, Huppa JB. Brameshuber M, et al. Among authors: huppa jb. Nat Immunol. 2018 May;19(5):487-496. doi: 10.1038/s41590-018-0092-4. Epub 2018 Apr 16. Nat Immunol. 2018. PMID: 29662172 Free PMC article.
Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances.
Ohradanova-Repic A, Machacek C, Charvet C, Lager F, Le Roux D, Platzer R, Leksa V, Mitulovic G, Burkard TR, Zlabinger GJ, Fischer MB, Feuillet V, Renault G, Blüml S, Benko M, Suchanek M, Huppa JB, Matsuyama T, Cavaco-Paulo A, Bismuth G, Stockinger H. Ohradanova-Repic A, et al. Among authors: huppa jb. Front Immunol. 2018 Apr 27;9:852. doi: 10.3389/fimmu.2018.00852. eCollection 2018. Front Immunol. 2018. PMID: 29780382 Free PMC article.
How drag sharpens a T cell's view on antigen.
Schütz GJ, Huppa JB. Schütz GJ, et al. Among authors: huppa jb. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16669-16671. doi: 10.1073/pnas.1911389116. Epub 2019 Aug 1. Proc Natl Acad Sci U S A. 2019. PMID: 31371492 Free PMC article. No abstract available.
73 results