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Postoperative risk of IDH-mutant glioma-associated seizures and their potential management with IDH-mutant inhibitors.
J Clin Invest. 2023 Jun 15;133(12):e168035. doi: 10.1172/JCI168035.
J Clin Invest. 2023.
PMID: 37104042
Free PMC article.
R132H IDH1 sensitizes glioma to the antiproliferative and cytotoxic effects of BET inhibition.
Sears TK, Woolard KD.
Sears TK, et al.
J Cancer Res Clin Oncol. 2022 Sep;148(9):2275-2285. doi: 10.1007/s00432-022-04018-w. Epub 2022 Apr 25.
J Cancer Res Clin Oncol. 2022.
PMID: 35467128
Free PMC article.
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Panobinostat Effectively Increases Histone Acetylation and Alters Chromatin Accessibility Landscape in Canine Embryonic Fibroblasts but Does Not Enhance Cellular Reprogramming.
Moshref M, Questa M, Lopez-Cervantes V, Sears TK, Greathouse RL, Crawford CK, Kol A.
Moshref M, et al. Among authors: sears tk.
Front Vet Sci. 2021 Sep 29;8:716570. doi: 10.3389/fvets.2021.716570. eCollection 2021.
Front Vet Sci. 2021.
PMID: 34660761
Free PMC article.
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IDH1 mutant glioma is preferentially sensitive to the HDAC inhibitor panobinostat.
Sears TK, Horbinski CM, Woolard KD.
Sears TK, et al.
J Neurooncol. 2021 Sep;154(2):159-170. doi: 10.1007/s11060-021-03829-0. Epub 2021 Aug 23.
J Neurooncol. 2021.
PMID: 34424450
Free PMC article.
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The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer.
Sears TK, Angelastro JM.
Sears TK, et al.
Oncotarget. 2017 Sep 20;8(48):84595-84609. doi: 10.18632/oncotarget.21102. eCollection 2017 Oct 13.
Oncotarget. 2017.
PMID: 29137451
Free PMC article.
Review.
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