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A Photolabile Curcumin-Diazirine Analogue Enables Phototherapy with Physically and Molecularly Produced Light for Alzheimer's Disease Treatment.
Kuang S, Zhu B, Zhang J, Yang F, Wu B, Ding W, Yang L, Shen S, Liang SH, Mondal P, Kumar M, Tanzi RE, Zhang C, Chao H, Ran C. Kuang S, et al. Among authors: tanzi re. Angew Chem Int Ed Engl. 2023 Nov 6;62(45):e202312519. doi: 10.1002/anie.202312519. Epub 2023 Sep 27. Angew Chem Int Ed Engl. 2023. PMID: 37721455
Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice.
Bai P, Liu Y, Yang L, Ding W, Mondal P, Sang N, Liu G, Lu X, Ho TT, Zhou Y, Wu R, Birar VC, Wilks MQ, Tanzi RE, Lin H, Zhang C, Li W, Shen S, Wang C. Bai P, et al. Among authors: tanzi re. J Med Chem. 2023 Dec 14;66(23):16075-16090. doi: 10.1021/acs.jmedchem.3c01491. Epub 2023 Nov 16. J Med Chem. 2023. PMID: 37972387
Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.
Bosch ME, Dodiya HB, Michalkiewicz J, Lee C, Shaik SM, Weigle IQ, Zhang C, Osborn J, Nambiar A, Patel P, Parhizkar S, Zhang X, Laury ML, Mondal P, Gomm A, Schipma MJ, Mallah D, Butovsky O, Chang EB, Tanzi RE, Gilbert JA, Holtzman DM, Sisodia SS. Bosch ME, et al. Among authors: tanzi re. Mol Neurodegener. 2024 Feb 17;19(1):18. doi: 10.1186/s13024-023-00700-w. Mol Neurodegener. 2024. PMID: 38365827 Free PMC article.
Accelerating the in vitro emulation of Alzheimer's disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model.
Ko EC, Spitz S, Pramotton FM, Barr OM, Xu C, Pavlou G, Zhang S, Tsai A, Maaser-Hecker A, Jorfi M, Choi SH, Tanzi RE, Kamm RD. Ko EC, et al. Among authors: tanzi re. Front Bioeng Biotechnol. 2023 Oct 9;11:1251195. doi: 10.3389/fbioe.2023.1251195. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 37901842 Free PMC article.
523 results