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Amino acid substitution L232F in non-structural protein 6 identified as a possible human-adaptive mutation in clade B MERS coronaviruses.
So RTY, Chu DKW, Hui KPY, Mok CKP, Shum MHH, Sanyal S, Nicholls JM, Ho JCW, Cheung M-c, Ng K-c, Yeung H-W, Chan MCW, Poon LLM, Zhao J, Lam TTY, Peiris M. So RTY, et al. Among authors: nicholls jm. J Virol. 2023 Dec 21;97(12):e0136923. doi: 10.1128/jvi.01369-23. Epub 2023 Dec 1. J Virol. 2023. PMID: 38038429 Free PMC article.
Erratum for Chan et al., "Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures".
Chan RWY, Chan MCW, Agnihothram S, Chan LLY, Kuok DIT, Fong JHM, Guan Y, Poon LLM, Baric RS, Nicholls JM, Peiris JSM. Chan RWY, et al. Among authors: nicholls jm. J Virol. 2024 Apr 16;98(4):e0037924. doi: 10.1128/jvi.00379-24. Epub 2024 Mar 18. J Virol. 2024. PMID: 38497665 Free PMC article. No abstract available.
Mutation nsp6 L232F associated with MERS-CoV zoonotic transmission confers higher viral replication in human respiratory tract cultures ex-vivo.
So RT, Chu DK, Hui KP, Mok CK, Sanyal S, Nicholls JM, Ho JCW, Cheung MC, Ng KC, Yeung HW, Chan MC, Poon LL, Zhao J, Peiris M. So RT, et al. Among authors: nicholls jm. bioRxiv [Preprint]. 2023 Mar 28:2023.03.27.534490. doi: 10.1101/2023.03.27.534490. bioRxiv. 2023. PMID: 37034576 Free PMC article. Updated. Preprint.
189 results