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Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian.
van den Akker EB, Makrodimitris S, Hulsman M, Brugman MH, Nikolic T, Bradley T, Waisfisz Q, Baas F, Jakobs ME, de Jong D, Slagboom PE, Staal FJT, Reinders MJT, Holstege H. van den Akker EB, et al. Leukemia. 2021 Jul;35(7):2125-2129. doi: 10.1038/s41375-020-01086-0. Epub 2020 Nov 12. Leukemia. 2021. PMID: 33184493 Free PMC article. No abstract available.
Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus.
Cordes M, Canté-Barrett K, van den Akker EB, Moretti FA, Kiełbasa SM, Vloemans SA, Garcia-Perez L, Teodosio C, van Dongen JJM, Pike-Overzet K, Reinders MJT, Staal FJT. Cordes M, et al. Among authors: van den akker eb, van dongen jjm. Sci Immunol. 2022 Nov 18;7(77):eade0182. doi: 10.1126/sciimmunol.ade0182. Epub 2022 Nov 11. Sci Immunol. 2022. PMID: 36367948
Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging.
van den Akker EB, Passtoors WM, Jansen R, van Zwet EW, Goeman JJ, Hulsman M, Emilsson V, Perola M, Willemsen G, Penninx BW, Heijmans BT, Maier AB, Boomsma DI, Kok JN, Slagboom PE, Reinders MJ, Beekman M. van den Akker EB, et al. Among authors: van zwet ew. Aging Cell. 2014 Apr;13(2):216-25. doi: 10.1111/acel.12160. Epub 2013 Nov 19. Aging Cell. 2014. PMID: 24119000 Free PMC article.
T and NK Cells in IL2RG-Deficient Patient 50 Years After Hematopoietic Stem Cell Transplantation.
Melsen JE, van Ostaijen-Ten Dam MM, van den Akker EB, Welters MJP, Heezen KC, Pico-Knijnenburg I, Kolijn PM, Bredius RGM, van Doorn R, Langerak AW, Schilham MW, Lankester AC. Melsen JE, et al. Among authors: van den akker eb, van doorn r, van ostaijen ten dam mm. J Clin Immunol. 2022 Aug;42(6):1205-1222. doi: 10.1007/s10875-022-01279-5. Epub 2022 May 9. J Clin Immunol. 2022. PMID: 35527320 Free PMC article.
Clonal Hematopoiesis Analyses in Clinical, Epidemiologic, and Genetic Aging Studies to Unravel Underlying Mechanisms of Age-Related Dysfunction in Humans.
Walsh K, Raghavachari N, Kerr C, Bick AG, Cummings SR, Druley T, Dunbar CE, Genovese G, Goodell MA, Jaiswal S, Maciejewski J, Natarajan P, Shindyapina AV, Shuldiner AR, Van Den Akker EB, Vijg J. Walsh K, et al. Among authors: van den akker eb. Front Aging. 2022 Mar 8;3:841796. doi: 10.3389/fragi.2022.841796. eCollection 2022. Front Aging. 2022. PMID: 35821803 Free PMC article. Review.
75 results