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Highly specific σ2R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response.
Yousuf MS, Sahn JJ, Yang H, David ET, Shiers S, Mancilla Moreno M, Iketem J, Royer DM, Garcia CD, Zhang J, Hong VM, Mian SM, Ahmad A, Kolber BJ, Liebl DJ, Martin SF, Price TJ. Yousuf MS, et al. Among authors: sahn jj. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2306090120. doi: 10.1073/pnas.2306090120. Epub 2023 Dec 20. Proc Natl Acad Sci U S A. 2023. PMID: 38117854 Free PMC article.
Highly specific σ2R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response.
Yousuf MS, Sahn JJ, Yang H, David ET, Shiers S, Moreno MM, Iketem J, Royer DM, Garcia CD, Zhang J, Hong VM, Mian SM, Ahmad A, Kolber BJ, Liebl DJ, Martin SF, Price TJ. Yousuf MS, et al. Among authors: sahn jj. bioRxiv [Preprint]. 2023 Oct 17:2023.04.11.536439. doi: 10.1101/2023.04.11.536439. bioRxiv. 2023. PMID: 37090527 Free PMC article. Updated. Preprint.
σ2R/TMEM97 in retinal ganglion cell degeneration.
Wang H, Peng Z, Li Y, Sahn JJ, Hodges TR, Chou TH, Liu Q, Zhou X, Jiao S, Porciatti V, Liebl DJ, Martin SF, Wen R. Wang H, et al. Among authors: sahn jj. Sci Rep. 2022 Dec 1;12(1):20753. doi: 10.1038/s41598-022-24537-3. Sci Rep. 2022. PMID: 36456686 Free PMC article.
Targeting σ2R/TMEM97 with novel aminotetralins.
Wood MD, Sahn JJ, Martin SF. Wood MD, et al. Among authors: sahn jj. Eur J Med Chem. 2022 Dec 5;243:114696. doi: 10.1016/j.ejmech.2022.114696. Epub 2022 Aug 28. Eur J Med Chem. 2022. PMID: 36088757
25 results