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Discovery of novel CSF biomarkers to predict progression in dementia using machine learning.
Sci Rep. 2023 Apr 21;13(1):6531. doi: 10.1038/s41598-023-33045-x.
Sci Rep. 2023.
PMID: 37085545
Free PMC article.
CSF proteomic signature predicts progression to Alzheimer's disease dementia.
Vromen EM, Del Campo Milán M, Scheltens P, Teunissen CE, Visser PJ, Tijms BM.
Vromen EM, et al.
Alzheimers Dement (N Y). 2022 Feb 23;8(1):e12240. doi: 10.1002/trc2.12240. eCollection 2022.
Alzheimers Dement (N Y). 2022.
PMID: 35229020
Free PMC article.
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Biomarker A+T-: is this Alzheimer's disease or not? A combined CSF and pathology study.
Vromen EM, de Boer SCM, Teunissen CE, Rozemuller A, Sieben A, Bjerke M; Alzheimer’s Disease Neuroimaging Initiative; Visser PJ, Bouwman FH, Engelborghs S, Tijms BM.
Vromen EM, et al.
Brain. 2023 Mar 1;146(3):1166-1174. doi: 10.1093/brain/awac158.
Brain. 2023.
PMID: 35511164
Free PMC article.
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Cerebrospinal fluid proteomics in patients with Alzheimer's disease reveals five molecular subtypes with distinct genetic risk profiles.
Tijms BM, Vromen EM, Mjaavatten O, Holstege H, Reus LM, van der Lee S, Wesenhagen KEJ, Lorenzini L, Vermunt L, Venkatraghavan V, Tesi N, Tomassen J, den Braber A, Goossens J, Vanmechelen E, Barkhof F, Pijnenburg YAL, van der Flier WM, Teunissen CE, Berven FS, Visser PJ.
Tijms BM, et al. Among authors: vromen em.
Nat Aging. 2024 Jan;4(1):33-47. doi: 10.1038/s43587-023-00550-7. Epub 2024 Jan 9.
Nat Aging. 2024.
PMID: 38195725
Free PMC article.
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Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's disease.
Nordengen K, Kirsebom BE, Richter G, Pålhaugen L, Gísladóttir B, Siafarikas N, Nakling A, Rongve A, Bråthen G, Grøntvedt GR, Gonzalez F, Waterloo K, Sharma K, Karikari T, Vromen EM, Tijms BM, Visser PJ, Selnes P, Kramberger MG, Winblad B, Blennow K, Fladby T.
Nordengen K, et al. Among authors: vromen em.
J Neuroinflammation. 2023 Dec 13;20(1):298. doi: 10.1186/s12974-023-02973-w.
J Neuroinflammation. 2023.
PMID: 38093257
Free PMC article.
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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers.
Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin O, Bergh S, Bertram L, Biessels GJ, Blennow K, Blesa R, Boada M, Boland A, Buerger K, Carracedo Á, Cervera-Carles L, Chene G, Claassen JAHR, Debette S, Deleuze JF, de Deyn PP, Diehl-Schmid J, Djurovic S, Dols-Icardo O, Dufouil C, Duron E, Düzel E; EADB consortium; Fladby T, Fortea J, Frölich L, García-González P, Garcia-Martinez M, Giegling I, Goldhardt O, Gobom J, Grimmer T, Haapasalo A, Hampel H, Hanon O, Hausner L, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herukka SK, Holstege H, Jarholm J, Kern S, Knapskog AB, Koivisto AM, Kornhuber J, Kuulasmaa T, Lage C, Laske C, Leinonen V, Lewczuk P, Lleó A, de Munain AL, Lopez-Garcia S, Maier W, Marquié M, Mol MO, Montrreal L, Moreno F, Moreno-Grau S, Nicolas G, Nöthen MM, Orellana A, Pålhaugen L, Papma JM, Pasquier F, Perneczky R, Peters O, Pijnenburg YAL, Popp J, Posthuma D, Pozueta A, Priller J, Puerta R, Quintela I, Ramaker…
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Jansen IE, et al. Among authors: vromen em.
Acta Neuropathol. 2022 Nov;144(5):821-842. doi: 10.1007/s00401-022-02454-z. Epub 2022 Sep 6.
Acta Neuropathol. 2022.
PMID: 36066633
Free PMC article.
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Grey matter network markers identify individuals with prodromal Alzheimer's disease who will show rapid clinical decline.
Pelkmans W, Vromen EM, Dicks E, Scheltens P, Teunissen CE, Barkhof F, van der Flier WM, Tijms BM; Alzheimer’s Disease Neuroimaging Initiative.
Pelkmans W, et al. Among authors: vromen em.
Brain Commun. 2022 Feb 8;4(2):fcac026. doi: 10.1093/braincomms/fcac026. eCollection 2022.
Brain Commun. 2022.
PMID: 35310828
Free PMC article.
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