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CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation.
Quandt E, Masip N, Hernández-Ortega S, Sánchez-Botet A, Gasa L, Fernández-Elorduy A, Plutta S, Martínez-Láinez JM, Bru S, Munoz-Torres PM, Floor M, Villà-Freixa J, Morris MC, Vidal A, Villanueva A, Clotet J, Ribeiro MPC. Quandt E, et al. Among authors: clotet j. Mol Oncol. 2023 Jul;17(7):1228-1245. doi: 10.1002/1878-0261.13438. Epub 2023 May 31. Mol Oncol. 2023. PMID: 37081792 Free PMC article.
The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration.
Sánchez-Botet A, Gasa L, Quandt E, Hernández-Ortega S, Jiménez J, Mezquita P, Carrasco-García MÀ, Kron SJ, Vidal A, Villanueva A, Ribeiro MPC, Clotet J. Sánchez-Botet A, et al. Among authors: clotet j. Sci Rep. 2018 Aug 7;8(1):11797. doi: 10.1038/s41598-018-30307-x. Sci Rep. 2018. PMID: 30087414 Free PMC article.
Atypical cyclin P regulates cancer cell stemness through activation of the WNT pathway.
Sánchez-Botet A, Quandt E, Masip N, Escribá R, Novellasdemunt L, Gasa L, Li VSW, Raya Á, Clotet J, Ribeiro MPC. Sánchez-Botet A, et al. Among authors: clotet j. Cell Oncol (Dordr). 2021 Dec;44(6):1273-1286. doi: 10.1007/s13402-021-00636-7. Epub 2021 Oct 4. Cell Oncol (Dordr). 2021. PMID: 34604945 Free PMC article.
Phosphate: from stardust to eukaryotic cell cycle control.
Jiménez J, Bru S, Ribeiro MP, Clotet J. Jiménez J, et al. Among authors: clotet j. Int Microbiol. 2016 Sep;19(3):133-141. doi: 10.2436/20.1501.01.271. Int Microbiol. 2016. PMID: 28494083 Free article. Review.
Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex.
Hernández-Ortega S, Sánchez-Botet A, Quandt E, Masip N, Gasa L, Verde G, Jiménez J, Levin RS, Rutaganira FU, Burlingame AL, Wolfgeher D, Ribeiro MPC, Kron SJ, Shokat KM, Clotet J. Hernández-Ortega S, et al. Among authors: clotet j. Exp Mol Med. 2019 Apr 16;51(4):1-17. doi: 10.1038/s12276-019-0242-2. Exp Mol Med. 2019. PMID: 30992425 Free PMC article.
Atypical cyclins: the extended family portrait.
Quandt E, Ribeiro MPC, Clotet J. Quandt E, et al. Among authors: clotet j. Cell Mol Life Sci. 2020 Jan;77(2):231-242. doi: 10.1007/s00018-019-03262-7. Epub 2019 Aug 16. Cell Mol Life Sci. 2020. PMID: 31420702 Free PMC article. Review.
Atypical cyclins in cancer: New kids on the block?
Quandt E, Ribeiro MPC, Clotet J. Quandt E, et al. Among authors: clotet j. Semin Cell Dev Biol. 2020 Nov;107:46-53. doi: 10.1016/j.semcdb.2020.04.018. Epub 2020 May 14. Semin Cell Dev Biol. 2020. PMID: 32417219 Review.
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