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Structural basis of centromeric cohesion protection.
García-Nieto A, Patel A, Li Y, Oldenkamp R, Feletto L, Graham JJ, Willems L, Muir KW, Panne D, Rowland BD. García-Nieto A, et al. Among authors: willems l. Nat Struct Mol Biol. 2023 Jun;30(6):853-859. doi: 10.1038/s41594-023-00968-y. Epub 2023 Apr 20. Nat Struct Mol Biol. 2023. PMID: 37081319 Free PMC article.
The structural basis for cohesin-CTCF-anchored loops.
Li Y, Haarhuis JHI, Sedeño Cacciatore Á, Oldenkamp R, van Ruiten MS, Willems L, Teunissen H, Muir KW, de Wit E, Rowland BD, Panne D. Li Y, et al. Among authors: willems l. Nature. 2020 Feb;578(7795):472-476. doi: 10.1038/s41586-019-1910-z. Epub 2020 Jan 6. Nature. 2020. PMID: 31905366 Free PMC article.
The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism.
van Ruiten MS, van Gent D, Sedeño Cacciatore Á, Fauster A, Willems L, Hekkelman ML, Hoekman L, Altelaar M, Haarhuis JHI, Brummelkamp TR, de Wit E, Rowland BD. van Ruiten MS, et al. Among authors: willems l. Nat Struct Mol Biol. 2022 Jun;29(6):586-591. doi: 10.1038/s41594-022-00773-z. Epub 2022 Jun 16. Nat Struct Mol Biol. 2022. PMID: 35710836 Free PMC article.
A Mediator-cohesin axis controls heterochromatin domain formation.
Haarhuis JHI, van der Weide RH, Blomen VA, Flach KD, Teunissen H, Willems L, Brummelkamp TR, Rowland BD, de Wit E. Haarhuis JHI, et al. Among authors: willems l. Nat Commun. 2022 Feb 8;13(1):754. doi: 10.1038/s41467-022-28377-7. Nat Commun. 2022. PMID: 35136067 Free PMC article.
A multicenter, matched case-control analysis comparing burden of illness among patients with tuberous sclerosis complex related epilepsy, generalized idiopathic epilepsy, and focal epilepsy in Germany.
Lappe L, Hertzberg C, Knake S, Knuf M, von Podewils F, Willems LM, Kovac S, Zöllner JP, Sauter M, Kurlemann G, Mayer T, Bertsche A, Marquard K, Meyer S, Schäfer H, Thiels C, Zukunft B, Schubert-Bast S, Reese JP, Rosenow F, Strzelczyk A. Lappe L, et al. Among authors: willems lm. Neurol Res Pract. 2024 May 30;6(1):29. doi: 10.1186/s42466-024-00323-6. Neurol Res Pract. 2024. PMID: 38812055 Free PMC article.
Harnessing beta cell regeneration biology for diabetes therapy.
Bourgeois S, Coenen S, Degroote L, Willems L, Van Mulders A, Pierreux J, Heremans Y, De Leu N, Staels W. Bourgeois S, et al. Among authors: willems l. Trends Endocrinol Metab. 2024 Apr 20:S1043-2760(24)00082-1. doi: 10.1016/j.tem.2024.03.006. Online ahead of print. Trends Endocrinol Metab. 2024. PMID: 38644094 Free article. Review.
Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation.
Rombaut D, Lefèvre C, Rached T, Bondu S, Letessier A, Mangione RM, Farhat B, Lesieur-Pasquier A, Castillo-Guzman D, Boussaid I, Friedrich C, Tourville A, De Carvalho M, Levavasseur F, Leduc M, Le Gall M, Battault S, Temple M, Houy A, Bouscary D, Willems L, Park S, Raynaud S, Cluzeau T, Clappier E, Fenaux P, Adès L, Margueron R, Wassef M, Alsafadi S, Chapuis N, Kosmider O, Solary E, Constantinou A, Stern MH, Droin N, Palancade B, Miotto B, Chédin F, Fontenay M. Rombaut D, et al. Among authors: willems l. Nat Commun. 2024 Apr 8;15(1):3016. doi: 10.1038/s41467-024-46547-7. Nat Commun. 2024. PMID: 38589367 Free PMC article.
CAR T-cell therapy induces a high rate of prolonged remission in relapsed primary CNS lymphoma: Real-life results of the LOC network.
Choquet S, Soussain C, Azar N, Morel V, Metz C, Ursu R, Waultier-Rascalou A, di Blasi R, Houot R, Souchet L, Roos-Weil D, Uzunov M, Quoc SN, Jacque N, Boussen I, Gauthier N, Ouzegdouh M, Blonski M, Campidelli A, Ahle G, Guffroy B, Willems L, Corvilain E, Barrie M, Alcantara M, le Garff-Tavernier M, Psimaras D, Weiss N, Baron M, Bravetti C, Hoang-Xuan K, Davi F, Shor N, Alentorn A, Houillier C. Choquet S, et al. Among authors: willems l. Am J Hematol. 2024 Apr 8. doi: 10.1002/ajh.27316. Online ahead of print. Am J Hematol. 2024. PMID: 38586986
Loss of hematopoietic progenitors heterogeneity is an adverse prognostic factor in lower-risk myelodysplastic neoplasms.
Dussiau C, Comont T, Knosp C, Vergnolle I, Bravetti C, Canali A, Houvert A, Largeaud L, Daveaux C, Zaroili L, Friedrich C, Boussaid I, Zalmai L, Almire C, Rauzy O, Willems L, Birsen R, Bouscary D, Fontenay M, Kosmider O, Chapuis N, Vergez F. Dussiau C, et al. Among authors: willems l. Leukemia. 2024 May;38(5):1131-1142. doi: 10.1038/s41375-024-02234-6. Epub 2024 Apr 4. Leukemia. 2024. PMID: 38575672 Free PMC article.
599 results