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The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells.
de Zeeuw P, Treps L, García-Caballero M, Harjes U, Kalucka J, De Legher C, Brepoels K, Peeters K, Vinckier S, Souffreau J, Bouché A, Taverna F, Dehairs J, Talebi A, Ghesquière B, Swinnen J, Schoonjans L, Eelen G, Dewerchin M, Carmeliet P. de Zeeuw P, et al. Among authors: vinckier s. Commun Biol. 2024 May 23;7(1):618. doi: 10.1038/s42003-024-06186-6. Commun Biol. 2024. PMID: 38783087 Free PMC article.
The murine retinal pigment epithelium requires peroxisomal β-oxidation to maintain lysosomal function and prevent dedifferentiation.
Kocherlakota S, Das Y, Swinkels D, Vanmunster M, Callens M, Vinckier S, Vaz FM, Sinha D, Van Veldhoven PP, Fransen M, Baes M. Kocherlakota S, et al. Among authors: vinckier s. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2301733120. doi: 10.1073/pnas.2301733120. Epub 2023 Oct 20. Proc Natl Acad Sci U S A. 2023. PMID: 37862382 Free PMC article.
VEGF Mediates Commissural Axon Chemoattraction through Its Receptor Flk1.
Ruiz de Almodovar C, Fabre PJ, Knevels E, Coulon C, Segura I, Haddick PCG, Aerts L, Delattin N, Strasser G, Oh WJ, Lange C, Vinckier S, Haigh J, Fouquet C, Gu C, Alitalo K, Castellani V, Tessier-Lavigne M, Chedotal A, Charron F, Carmeliet P. Ruiz de Almodovar C, et al. Among authors: vinckier s. Neuron. 2023 Apr 19;111(8):1348. doi: 10.1016/j.neuron.2023.03.029. Neuron. 2023. PMID: 37080170 Free article. No abstract available.
Generation of vessel co-option lung metastases mouse models for single-cell isolation of metastases-derived cells and endothelial cells.
Cuypers A, Teuwen LA, Bridgeman VL, de Rooij LPMH, Eelen G, Dewerchin M, Cantelmo AR, Kalucka J, Bouché A, Vinckier S, Carton A, Manderveld A, Vermeulen PB, Reynolds AR, Carmeliet P. Cuypers A, et al. Among authors: vinckier s. STAR Protoc. 2022 Dec 16;3(4):101691. doi: 10.1016/j.xpro.2022.101691. Epub 2022 Sep 28. STAR Protoc. 2022. PMID: 36173713 Free PMC article.
Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast.
Geldhof V, de Rooij LPMH, Sokol L, Amersfoort J, De Schepper M, Rohlenova K, Hoste G, Vanderstichele A, Delsupehe AM, Isnaldi E, Dai N, Taverna F, Khan S, Truong AK, Teuwen LA, Richard F, Treps L, Smeets A, Nevelsteen I, Weynand B, Vinckier S, Schoonjans L, Kalucka J, Desmedt C, Neven P, Mazzone M, Floris G, Punie K, Dewerchin M, Eelen G, Wildiers H, Li X, Luo Y, Carmeliet P. Geldhof V, et al. Among authors: vinckier s. Nat Commun. 2022 Sep 20;13(1):5511. doi: 10.1038/s41467-022-33052-y. Nat Commun. 2022. PMID: 36127427 Free PMC article.
The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution.
de Rooij LPMH, Becker LM, Teuwen LA, Boeckx B, Jansen S, Feys S, Verleden S, Liesenborghs L, Stalder AK, Libbrecht S, Van Buyten T, Philips G, Subramanian A, Dumas SJ, Meta E, Borri M, Sokol L, Dendooven A, Truong AK, Gunst J, Van Mol P, Haslbauer JD, Rohlenova K, Menter T, Boudewijns R, Geldhof V, Vinckier S, Amersfoort J, Wuyts W, Van Raemdonck D, Jacobs W, Ceulemans LJ, Weynand B, Thienpont B, Lammens M, Kuehnel M, Eelen G, Dewerchin M, Schoonjans L, Jonigk D, van Dorpe J, Tzankov A, Wauters E, Mazzone M, Neyts J, Wauters J, Lambrechts D, Carmeliet P. de Rooij LPMH, et al. Among authors: vinckier s. Cardiovasc Res. 2023 Mar 31;119(2):520-535. doi: 10.1093/cvr/cvac139. Cardiovasc Res. 2023. PMID: 35998078 Free PMC article.
Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.
Meçe O, Houbaert D, Sassano ML, Durré T, Maes H, Schaaf M, More S, Ganne M, García-Caballero M, Borri M, Verhoeven J, Agrawal M, Jacobs K, Bergers G, Blacher S, Ghesquière B, Dewerchin M, Swinnen JV, Vinckier S, Soengas MS, Carmeliet P, Noël A, Agostinis P. Meçe O, et al. Among authors: vinckier s. Nat Commun. 2022 May 19;13(1):2760. doi: 10.1038/s41467-022-30490-6. Nat Commun. 2022. PMID: 35589749 Free PMC article.
70 results