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Exo1 protects DNA nicks from ligation to promote crossover formation during meiosis.
PLoS Biol. 2023 Apr 20;21(4):e3002085. doi: 10.1371/journal.pbio.3002085. eCollection 2023 Apr.
PLoS Biol. 2023.
PMID: 37079643
Free PMC article.
Coordinated and Independent Roles for MLH Subunits in DNA Repair.
Pannafino G, Alani E.
Pannafino G, et al.
Cells. 2021 Apr 20;10(4):948. doi: 10.3390/cells10040948.
Cells. 2021.
PMID: 33923939
Free PMC article.
Review.
Item in Clipboard
Experimental exchange of paralogous domains in the MLH family provides evidence of sub-functionalization after gene duplication.
Furman CM, Elbashir R, Pannafino G, Clark NL, Alani E.
Furman CM, et al. Among authors: pannafino g.
G3 (Bethesda). 2021 Jun 17;11(6):jkab111. doi: 10.1093/g3journal/jkab111.
G3 (Bethesda). 2021.
PMID: 33871573
Free PMC article.
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Human MLH1/3 variants causing aneuploidy, pregnancy loss, and premature reproductive aging.
Singh P, Fragoza R, Blengini CS, Tran TN, Pannafino G, Al-Sweel N, Schimenti KJ, Schindler K, Alani EA, Yu H, Schimenti JC.
Singh P, et al. Among authors: pannafino g.
Nat Commun. 2021 Aug 18;12(1):5005. doi: 10.1038/s41467-021-25028-1.
Nat Commun. 2021.
PMID: 34408140
Free PMC article.
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The Dmc1 recombinase physically interacts with and promotes the meiotic crossover functions of the Mlh1-Mlh3 endonuclease.
Pannafino G, Chen JJ, Mithani V, Payero L, Gioia M, Crickard JB, Alani E.
Pannafino G, et al.
Genetics. 2024 Apr 24:iyae066. doi: 10.1093/genetics/iyae066. Online ahead of print.
Genetics. 2024.
PMID: 38657110
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The Dmc1 recombinase physically interacts with and promotes the meiotic crossover functions of the Mlh1-Mlh3 endonuclease.
Pannafino G, Chen JJ, Mithani V, Payero L, Gioia M, Brooks Crickard J, Alani E.
Pannafino G, et al.
bioRxiv [Preprint]. 2023 Nov 13:2023.11.13.566911. doi: 10.1101/2023.11.13.566911.
bioRxiv. 2023.
PMID: 38014100
Free PMC article.
Updated.
Preprint.
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Treacher Collins syndrome mutations in Saccharomyces cerevisiae destabilize RNA polymerase I and III complex integrity.
Walker-Kopp N, Jackobel AJ, Pannafino GN, Morocho PA, Xu X, Knutson BA.
Walker-Kopp N, et al. Among authors: pannafino gn.
Hum Mol Genet. 2017 Nov 1;26(21):4290-4300. doi: 10.1093/hmg/ddx317.
Hum Mol Genet. 2017.
PMID: 28973381
Free PMC article.
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