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Page 1
Mechanical thrombectomy in acute limb ischemia: ad Interim results of the INDIAN UP Trial.
de Donato G, Pasqui E, Ruffino MA, Sponza M, Spinazzola A, Guzzardi G, Intrieri F, Savio D, Palasciano G; INDIAN UP Trial group. de Donato G, et al. Among authors: spinazzola a. J Cardiovasc Surg (Torino). 2023 Jun;64(3):247-254. doi: 10.23736/S0021-9509.23.12668-1. Epub 2023 Apr 20. J Cardiovasc Surg (Torino). 2023. PMID: 37078985 Free article.
Penumbra Indigo Percutaneous Aspiration Thrombectomy System in the treatment of Aortic Endograft Iliac Limb Occlusion: Results from an Italian Multicentre Registry.
Spath P, Pasqui E, Angiletta D, Spinazzola A, Chegai F, Isernia G, Lepidi S, Silingardi R, de Donato G, Gargiulo M; Italian Multicentre Thrombo-Aspiration in ILO Study Group. Spath P, et al. Among authors: spinazzola a. Eur J Vasc Endovasc Surg. 2023 Jul;66(1):77-84. doi: 10.1016/j.ejvs.2023.04.008. Epub 2023 Apr 20. Eur J Vasc Endovasc Surg. 2023. PMID: 37084878 Free article.
Mitochondrial DNA competition: starving out the mutant genome.
Spinazzola A, Perez-Rodriguez D, Ježek J, Holt IJ. Spinazzola A, et al. Trends Pharmacol Sci. 2024 Mar;45(3):225-242. doi: 10.1016/j.tips.2024.01.011. Epub 2024 Feb 23. Trends Pharmacol Sci. 2024. PMID: 38402076 Free article. Review.
Elevated cholesterol in ATAD3 mutants is a compensatory mechanism that leads to membrane cholesterol aggregation.
Muñoz-Oreja M, Sandoval A, Bruland O, Perez-Rodriguez D, Fernandez-Pelayo U, de Arbina AL, Villar-Fernandez M, Hernández-Eguiazu H, Hernández I, Park Y, Goicoechea L, Pascual-Frías N, Garcia-Ruiz C, Fernandez-Checa J, Martí-Carrera I, Gil-Bea FJ, Hasan MT, Gegg ME, Bredrup C, Knappskog PM, Gereñu-Lopetegui G, Varhaug KN, Bindoff LA, Spinazzola A, Yoon WH, Holt IJ. Muñoz-Oreja M, et al. Among authors: spinazzola a. Brain. 2024 May 3;147(5):1899-1913. doi: 10.1093/brain/awae018. Brain. 2024. PMID: 38242545 Free PMC article.
Bi-allelic LETM1 variants perturb mitochondrial ion homeostasis leading to a clinical spectrum with predominant nervous system involvement.
Kaiyrzhanov R, Mohammed SEM, Maroofian R, Husain RA, Catania A, Torraco A, Alahmad A, Dutra-Clarke M, Grønborg S, Sudarsanam A, Vogt J, Arrigoni F, Baptista J, Haider S, Feichtinger RG, Bernardi P, Zulian A, Gusic M, Efthymiou S, Bai R, Bibi F, Horga A, Martinez-Agosto JA, Lam A, Manole A, Rodriguez DP, Durigon R, Pyle A, Albash B, Dionisi-Vici C, Murphy D, Martinelli D, Bugiardini E, Allis K, Lamperti C, Reipert S, Risom L, Laugwitz L, Di Nottia M, McFarland R, Vilarinho L, Hanna M, Prokisch H, Mayr JA, Bertini ES, Ghezzi D, Østergaard E, Wortmann SB, Carrozzo R, Haack TB, Taylor RW, Spinazzola A, Nowikovsky K, Houlden H. Kaiyrzhanov R, et al. Among authors: spinazzola a. Am J Hum Genet. 2022 Sep 1;109(9):1692-1712. doi: 10.1016/j.ajhg.2022.07.007. Am J Hum Genet. 2022. PMID: 36055214 Free PMC article.
2 deoxy-D-glucose augments the mitochondrial respiratory chain in heart.
Aiestaran-Zelaia I, Sánchez-Guisado MJ, Villar-Fernandez M, Azkargorta M, Fadon-Padilla L, Fernandez-Pelayo U, Perez-Rodriguez D, Ramos-Cabrer P, Spinazzola A, Elortza F, Ruíz-Cabello J, Holt IJ. Aiestaran-Zelaia I, et al. Among authors: spinazzola a. Sci Rep. 2022 Apr 27;12(1):6890. doi: 10.1038/s41598-022-10168-1. Sci Rep. 2022. PMID: 35478201 Free PMC article.
2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA.
Pantic B, Ives D, Mennuni M, Perez-Rodriguez D, Fernandez-Pelayo U, Lopez de Arbina A, Muñoz-Oreja M, Villar-Fernandez M, Dang TJ, Vergani L, Johnston IG, Pitceathly RDS, McFarland R, Hanna MG, Taylor RW, Holt IJ, Spinazzola A. Pantic B, et al. Among authors: spinazzola a. Nat Commun. 2021 Dec 6;12(1):6997. doi: 10.1038/s41467-021-26829-0. Nat Commun. 2021. PMID: 34873176 Free PMC article.
157 results