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Mechanistic Pharmacokinetic/Pharmacodynamic Modeling in Support of a Patient-Convenient, Longer Dosing Interval for Carfilzomib, a Covalent Inhibitor of the Proteasome.
Clin Pharmacokinet. 2023 May;62(5):779-788. doi: 10.1007/s40262-023-01242-6. Epub 2023 Apr 18.
Clin Pharmacokinet. 2023.
PMID: 37072559
Free PMC article.
Clinical Trial.
Recent advances and clinical pharmacology aspects of Chimeric Antigen Receptor (CAR) T-cellular therapy development.
Kast J, Nozohouri S, Zhou D, Yago MR, Chen PW, Ahamadi M, Dutta S, Upreti VV.
Kast J, et al. Among authors: yago mr.
Clin Transl Sci. 2022 Sep;15(9):2057-2074. doi: 10.1111/cts.13349. Epub 2022 Jul 2.
Clin Transl Sci. 2022.
PMID: 35677992
Free PMC article.
Review.
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Drug absorption interactions between oral targeted anticancer agents and PPIs: is pH-dependent solubility the Achilles heel of targeted therapy?
Budha NR, Frymoyer A, Smelick GS, Jin JY, Yago MR, Dresser MJ, Holden SN, Benet LZ, Ware JA.
Budha NR, et al. Among authors: yago mr.
Clin Pharmacol Ther. 2012 Aug;92(2):203-13. doi: 10.1038/clpt.2012.73. Epub 2012 Jun 27.
Clin Pharmacol Ther. 2012.
PMID: 22739140
Review.
Item in Clipboard
Safety and tolerability of AMG 330 in adults with relapsed/refractory AML: a phase 1a dose-escalation study.
Ravandi F, Subklewe M, Walter RB, Vachhani P, Ossenkoppele G, Buecklein V, Döhner H, Jongen-Lavrencic M, Baldus CD, Fransecky L, Pardee TS, Kantarjian H, Yen PK, Mukundan L, Panwar B, Yago MR, Agarwal S, Khaldoyanidi SK, Stein A.
Ravandi F, et al. Among authors: yago mr.
Leuk Lymphoma. 2024 May 7:1-11. doi: 10.1080/10428194.2024.2346755. Online ahead of print.
Leuk Lymphoma. 2024.
PMID: 38712673
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Meal Effects Confound Attempts to Counteract Rabeprazole-Induced Hypochlorhydria Decreases in Atazanavir Absorption.
Faber KP, Wu HF, Yago MR, Xu X, Kadiyala P, Frassetto LA, Benet LZ.
Faber KP, et al. Among authors: yago mr.
Pharm Res. 2017 Mar;34(3):619-628. doi: 10.1007/s11095-016-2090-2. Epub 2016 Dec 27.
Pharm Res. 2017.
PMID: 28028768
Free PMC article.
Clinical Trial.
Item in Clipboard
The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria.
Yago MR, Frymoyer A, Benet LZ, Smelick GS, Frassetto LA, Ding X, Dean B, Salphati L, Budha N, Jin JY, Dresser MJ, Ware JA.
Yago MR, et al.
AAPS J. 2014 Nov;16(6):1358-65. doi: 10.1208/s12248-014-9673-9. Epub 2014 Oct 2.
AAPS J. 2014.
PMID: 25274610
Free PMC article.
Clinical Trial.
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Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria.
Yago MR, Frymoyer AR, Smelick GS, Frassetto LA, Budha NR, Dresser MJ, Ware JA, Benet LZ.
Yago MR, et al.
Mol Pharm. 2013 Nov 4;10(11):4032-7. doi: 10.1021/mp4003738. Epub 2013 Sep 10.
Mol Pharm. 2013.
PMID: 23980906
Free PMC article.
Clinical Trial.
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