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Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein.
Shum A, Zaichick S, McElroy GS, D'Alessandro K, Alasady MJ, Novakovic M, Peng W, Grebenik EA, Chung D, Flanagan ME, Smith R, Morales A, Stumpf L, McGrath K, Krainc D, Mendillo ML, Prakriya M, Chandel NS, Caraveo G. Shum A, et al. Among authors: flanagan me. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2217396120. doi: 10.1073/pnas.2217396120. Epub 2023 Apr 17. Proc Natl Acad Sci U S A. 2023. PMID: 37068235 Free PMC article.
Neuropathology of Anti-Amyloid-β Immunotherapy: A Case Report.
Castellani RJ, Shanes ED, McCord M, Reish NJ, Flanagan ME, Mesulam MM, Jamshidi P. Castellani RJ, et al. Among authors: flanagan me. J Alzheimers Dis. 2023;93(2):803-813. doi: 10.3233/JAD-221305. J Alzheimers Dis. 2023. PMID: 37125554
Genome sequence analyses identify novel risk loci for multiple system atrophy.
Chia R, Ray A, Shah Z, Ding J, Ruffo P, Fujita M, Menon V, Saez-Atienzar S, Reho P, Kaivola K, Walton RL, Reynolds RH, Karra R, Sait S, Akcimen F, Diez-Fairen M, Alvarez I, Fanciulli A, Stefanova N, Seppi K, Duerr S, Leys F, Krismer F, Sidoroff V, Zimprich A, Pirker W, Rascol O, Foubert-Samier A, Meissner WG, Tison F, Pavy-Le Traon A, Pellecchia MT, Barone P, Russillo MC, Marín-Lahoz J, Kulisevsky J, Torres S, Mir P, Periñán MT, Proukakis C, Chelban V, Wu L, Goh YY, Parkkinen L, Hu MT, Kobylecki C, Saxon JA, Rollinson S, Garland E, Biaggioni I, Litvan I, Rubio I, Alcalay RN, Kwei KT, Lubbe SJ, Mao Q, Flanagan ME, Castellani RJ, Khurana V, Ndayisaba A, Calvo A, Mora G, Canosa A, Floris G, Bohannan RC, Moore A, Norcliffe-Kaufmann L, Palma JA, Kaufmann H, Kim C, Iba M, Masliah E, Dawson TM, Rosenthal LS, Pantelyat A, Albert MS, Pletnikova O, Troncoso JC, Infante J, Lage C, Sánchez-Juan P, Serrano GE, Beach TG, Pastor P, Morris HR, Albani D, Clarimon J, Wenning GK, Hardy JA, Ryten M, Topol E, Torkamani A, Chiò A, Bennett DA, De Jager PL, Low PA, Singer W, Cheshire WP, Wszolek ZK, Dickson DW, Traynor BJ, Gibbs JR, Dalgard CL, Ross OA, Houlden H, Scholz SW. Chia R, et al. Among authors: flanagan me. Neuron. 2024 Apr 24:S0896-6273(24)00240-X. doi: 10.1016/j.neuron.2024.04.002. Online ahead of print. Neuron. 2024. PMID: 38701790 Free article.
Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias.
Kawles A, Keszycki R, Minogue G, Zouridakis A, Ayala I, Gill N, Macomber A, Lubbat V, Coventry C, Rogalski E, Weintraub S, Mao Q, Flanagan ME, Zhang H, Castellani R, Bigio EH, Mesulam MM, Geula C, Gefen T. Kawles A, et al. Among authors: flanagan me. Acta Neuropathol Commun. 2024 Feb 22;12(1):31. doi: 10.1186/s40478-024-01738-7. Acta Neuropathol Commun. 2024. PMID: 38389095 Free PMC article.
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease.
Xu J, Mao C, Hou Y, Luo Y, Binder JL, Zhou Y, Bekris LM, Shin J, Hu M, Wang F, Eng C, Oprea TI, Flanagan ME, Pieper AA, Cummings J, Leverenz JB, Cheng F. Xu J, et al. Among authors: flanagan me. Cell Rep. 2022 Nov 29;41(9):111717. doi: 10.1016/j.celrep.2022.111717. Cell Rep. 2022. PMID: 36450252 Free PMC article.
Differential vulnerability of the dentate gyrus to tauopathies in dementias.
Kawles A, Minogue G, Zouridakis A, Keszycki R, Gill N, Nassif C, Coventry C, Zhang H, Rogalski E, Flanagan ME, Castellani R, Bigio EH, Mesulam MM, Geula C, Gefen T. Kawles A, et al. Among authors: flanagan me. Acta Neuropathol Commun. 2023 Jan 3;11(1):1. doi: 10.1186/s40478-022-01485-7. Acta Neuropathol Commun. 2023. PMID: 36597124 Free PMC article.
163 results