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Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering.
Barnes MD, Winkler ML, Taracila MA, Page MG, Desarbre E, Kreiswirth BN, Shields RK, Nguyen MH, Clancy C, Spellberg B, Papp-Wallace KM, Bonomo RA. Barnes MD, et al. Among authors: bonomo ra. mBio. 2017 Oct 31;8(5):e00528-17. doi: 10.1128/mBio.00528-17. mBio. 2017. PMID: 29089425 Free PMC article.
Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent.
Barnes MD, Kumar V, Bethel CR, Moussa SH, O'Donnell J, Rutter JD, Good CE, Hujer KM, Hujer AM, Marshall SH, Kreiswirth BN, Richter SS, Rather PN, Jacobs MR, Papp-Wallace KM, van den Akker F, Bonomo RA. Barnes MD, et al. Among authors: bonomo ra. mBio. 2019 Mar 12;10(2):e00159-19. doi: 10.1128/mBio.00159-19. mBio. 2019. PMID: 30862744 Free PMC article.
Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae.
Kim TH, Tao X, Moya B, Jiao Y, Basso KB, Zhou J, Lang Y, Sutaria DS, Zavascki AP, Barth AL, Reeve SM, Schweizer HP, Deveson Lucas D, Boyce JD, Bonomo RA, Lee RE, Shin BS, Louie A, Drusano GL, Bulitta JB. Kim TH, et al. Among authors: bonomo ra. mBio. 2020 Feb 11;11(1):e03189-19. doi: 10.1128/mBio.03189-19. mBio. 2020. PMID: 32047131 Free PMC article.
723 results