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Development of subunit selective substrates for Trichomonas vaginalis proteasome.
Fajtova P, Hurysz BM, Miyamoto Y, Serafim M, Jiang Z, Trujillo DF, Liu L, Somani U, Almaliti J, Myers SA, Caffrey CR, Gerwick WH, Kirk CJ, Boura E, Eckmann L, O'Donoghue AJ. Fajtova P, et al. Among authors: jiang z. bioRxiv [Preprint]. 2023 Apr 6:2023.04.05.535794. doi: 10.1101/2023.04.05.535794. bioRxiv. 2023. PMID: 37066163 Free PMC article. Preprint.
Targeting proteasomes in infectious organisms to combat disease.
Bibo-Verdugo B, Jiang Z, Caffrey CR, O'Donoghue AJ. Bibo-Verdugo B, et al. Among authors: jiang z. FEBS J. 2017 May;284(10):1503-1517. doi: 10.1111/febs.14029. Epub 2017 Feb 16. FEBS J. 2017. PMID: 28122162 Free article. Review.
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties.
Leontovyč A, Ulrychová L, O'Donoghue AJ, Vondrášek J, Marešová L, Hubálek M, Fajtová P, Chanová M, Jiang Z, Craik CS, Caffrey CR, Mareš M, Dvořák J, Horn M. Leontovyč A, et al. Among authors: jiang z. PLoS Negl Trop Dis. 2018 Apr 20;12(4):e0006446. doi: 10.1371/journal.pntd.0006446. eCollection 2018 Apr. PLoS Negl Trop Dis. 2018. PMID: 29677188 Free PMC article.
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry.
Lapek JD Jr, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ. Lapek JD Jr, et al. Among authors: jiang z. Mol Cell Proteomics. 2019 May;18(5):968-981. doi: 10.1074/mcp.TIR118.001099. Epub 2019 Jan 31. Mol Cell Proteomics. 2019. PMID: 30705125 Free PMC article.
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni.
Bibo-Verdugo B, Wang SC, Almaliti J, Ta AP, Jiang Z, Wong DA, Lietz CB, Suzuki BM, El-Sakkary N, Hook V, Salvesen GS, Gerwick WH, Caffrey CR, O'Donoghue AJ. Bibo-Verdugo B, et al. Among authors: jiang z. ACS Infect Dis. 2019 Oct 11;5(10):1802-1812. doi: 10.1021/acsinfecdis.9b00237. Epub 2019 Aug 12. ACS Infect Dis. 2019. PMID: 31355632 Free PMC article.
20S Proteasome as a Drug Target in Trichomonas vaginalis.
O'Donoghue AJ, Bibo-Verdugo B, Miyamoto Y, Wang SC, Yang JZ, Zuill DE, Matsuka S, Jiang Z, Almaliti J, Caffrey CR, Gerwick WH, Eckmann L. O'Donoghue AJ, et al. Among authors: jiang z. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00448-19. doi: 10.1128/AAC.00448-19. Print 2019 Nov. Antimicrob Agents Chemother. 2019. PMID: 31451503 Free PMC article.
Multiplex substrate profiling by mass spectrometry for proteases.
Rohweder PJ, Jiang Z, Hurysz BM, O'Donoghue AJ, Craik CS. Rohweder PJ, et al. Among authors: jiang z. Methods Enzymol. 2023;682:375-411. doi: 10.1016/bs.mie.2022.09.009. Epub 2022 Dec 21. Methods Enzymol. 2023. PMID: 36948708 Free PMC article.
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