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Tracking of activated cTfh cells following sequential influenza vaccinations reveals transcriptional profile of clonotypes driving a vaccine-induced immune response.
Currenti J, Simmons J, Oakes J, Gaudieri S, Warren CM, Gangula R, Alves E, Ram R, Leary S, Armitage JD, Smith RM, Chopra A, Halasa NB, Pilkinton MA, Kalams SA. Currenti J, et al. Front Immunol. 2023 Mar 29;14:1133781. doi: 10.3389/fimmu.2023.1133781. eCollection 2023. Front Immunol. 2023. PMID: 37063867 Free PMC article.
Cross-Reactivity to Mutated Viral Immune Targets Can Influence CD8+ T Cell Functionality: An Alternative Viral Adaptation Strategy.
Currenti J, Law BMP, Qin K, John M, Pilkinton MA, Bansal A, Leary S, Ram R, Chopra A, Gangula R, Yue L, Warren C, Barnett L, Alves E, McDonnell WJ, Sooda A, Heath SL, Mallal S, Goepfert P, Kalams SA, Gaudieri S. Currenti J, et al. Front Immunol. 2021 Oct 26;12:746986. doi: 10.3389/fimmu.2021.746986. eCollection 2021. Front Immunol. 2021. PMID: 34764960 Free PMC article.
Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV.
Currenti J, Chopra A, John M, Leary S, McKinnon E, Alves E, Pilkinton M, Smith R, Barnett L, McDonnell WJ, Lucas M, Noel F, Mallal S, Conrad JA, Kalams SA, Gaudieri S. Currenti J, et al. PLoS Pathog. 2019 Dec 10;15(12):e1008177. doi: 10.1371/journal.ppat.1008177. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31821379 Free PMC article.
In chronic infection, HIV gag-specific CD4+ T cell receptor diversity is higher than CD8+ T cell receptor diversity and is associated with less HIV quasispecies diversity.
Pilkinton MA, McDonnell WJ, Barnett L, Chopra A, Gangula R, White KD, Leary S, Currenti J, Gaudieri S, Mallal SA, Kalams SA. Pilkinton MA, et al. Among authors: currenti j. J Virol. 2021 Mar 25;95(8):e02380-20. doi: 10.1128/JVI.02380-20. Epub 2021 Feb 3. J Virol. 2021. PMID: 33536169 Free PMC article.
Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy.
Li Z, Pai R, Gupta S, Currenti J, Guo W, Di Bartolomeo A, Feng H, Zhang Z, Li Z, Liu L, Singh A, Bai Y, Yang B, Mishra A, Yang K, Qiao L, Wallace M, Yin Y, Xia Q, Chan JKY, George J, Chow PK, Ginhoux F, Sharma A. Li Z, et al. Among authors: currenti j. Nat Cancer. 2024 Jan;5(1):167-186. doi: 10.1038/s43018-023-00672-2. Epub 2024 Jan 2. Nat Cancer. 2024. PMID: 38168935
Oncofetal reprogramming in tumour development and progression.
Sharma A, Blériot C, Currenti J, Ginhoux F. Sharma A, et al. Among authors: currenti j. Nat Rev Cancer. 2022 Oct;22(10):593-602. doi: 10.1038/s41568-022-00497-8. Epub 2022 Aug 23. Nat Rev Cancer. 2022. PMID: 35999292 Review.