Radinov R - Search Results

1

Convergent Biocatalytic Mediated Synthesis of siRNA.

Paul S, Gray D, Caswell J, Brooks J, Ye W, Moody TS, Radinov R, Nechev L. Paul S, et al. Among authors: radinov r. ACS Chem Biol. 2023 Oct 20;18(10):2183-2187. doi: 10.1021/acschembio.3c00071. Epub 2023 Apr 16. ACS Chem Biol. 2023. PMID: 37061926

2

Identification of RO4597014, a Glucokinase Activator Studied in the Clinic for the Treatment of Type 2 Diabetes.

Qian Y, Corbett WL, Berthel SJ, Choi DS, Dvorozniak MT, Geng W, Gillespie P, Guertin KR, Haynes NE, Kester RF, Mennona FA, Moore D, Racha J, Radinov R, Sarabu R, Scott NR, Grimsby J, Mallalieu NL. Qian Y, et al. Among authors: radinov r. ACS Med Chem Lett. 2013 Mar 7;4(4):414-8. doi: 10.1021/ml400027y. eCollection 2013 Apr 11. ACS Med Chem Lett. 2013. PMID: 24900686 Free PMC article.

3

Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients.

Sarabu R, Bizzarro FT, Corbett WL, Dvorozniak MT, Geng W, Grippo JF, Haynes NE, Hutchings S, Garofalo L, Guertin KR, Hilliard DW, Kabat M, Kester RF, Ka W, Liang Z, Mahaney PE, Marcus L, Matschinsky FM, Moore D, Racha J, Radinov R, Ren Y, Qi L, Pignatello M, Spence CL, Steele T, Tengi J, Grimsby J. Sarabu R, et al. Among authors: radinov r. J Med Chem. 2012 Aug 23;55(16):7021-36. doi: 10.1021/jm3008689. Epub 2012 Aug 1. J Med Chem. 2012. PMID: 22809456

4

The practical synthesis of vitamin D analogs: a challenge for process research.

Kabat MM, Radinov R. Kabat MM, et al. Among authors: radinov r. Curr Opin Drug Discov Devel. 2001 Nov;4(6):808-33. Curr Opin Drug Discov Devel. 2001. PMID: 11899621 Review.

5

Efficient synthesis of the A-ring phosphine oxide building block useful for 1 alpha,25-dihydroxy vitamin D(3) and analogues.

Daniewski AR, Garofalo LM, Hutchings SD, Kabat MM, Liu W, Okabe M, Radinov R, Yiannikouros GP. Daniewski AR, et al. Among authors: radinov r. J Org Chem. 2002 Mar 8;67(5):1580-7. doi: 10.1021/jo0161577. J Org Chem. 2002. PMID: 11871890

6

Efficient synthesis of 1alpha-fluoro A-ring phosphine oxide, a useful building block for vitamin D analogues, from (S)-carvone via a highly selective palladium-catalyzed isomerization of dieneoxide to dieneol.

Kabat MM, Garofalo LM, Daniewski AR, Hutchings SD, Liu W, Okabe M, Radinov R, Zhou Y. Kabat MM, et al. Among authors: radinov r. J Org Chem. 2001 Sep 7;66(18):6141-50. doi: 10.1021/jo015788y. J Org Chem. 2001. PMID: 11529743

7

Catalytic asymmetric synthesis of macrocyclic (E)-allylic alcohols from omega-alkynals via intramolecular 1-alkenylzinc/aldehyde additions.

Oppolzer W, Radinov RN, El-Sayed E. Oppolzer W, et al. Among authors: radinov rn. J Org Chem. 2001 Jul 13;66(14):4766-70. doi: 10.1021/jo000463n. J Org Chem. 2001. PMID: 11442401

8

Pyrido[4,3-e]-1,4-diazepines and pyrido[4,3-b]-1,5-benzodiazepines: synthesis and affinity to brain benzodiazepine receptors.

Radinov R, Haimova M, Simova E, Tyutyulkova N, Gorantcheva J. Radinov R, et al. Arch Pharm (Weinheim). 1987 Aug;320(8):704-10. doi: 10.1002/ardp.19873200807. Arch Pharm (Weinheim). 1987. PMID: 2823741 No abstract available.

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