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Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics.
Dans MG, Piirainen H, Nguyen W, Khurana S, Mehra S, Razook Z, Geoghegan ND, Dawson AT, Das S, Parkyn Schneider M, Jonsdottir TK, Gabriela M, Gancheva MR, Tonkin CJ, Mollard V, Goodman CD, McFadden GI, Wilson DW, Rogers KL, Barry AE, Crabb BS, de Koning-Ward TF, Sleebs BE, Kursula I, Gilson PR. Dans MG, et al. Among authors: geoghegan nd. PLoS Biol. 2023 Apr 13;21(4):e3002066. doi: 10.1371/journal.pbio.3002066. eCollection 2023 Apr. PLoS Biol. 2023. PMID: 37053271 Free PMC article.
Activation mechanism of PINK1.
Gan ZY, Callegari S, Cobbold SA, Cotton TR, Mlodzianoski MJ, Schubert AF, Geoghegan ND, Rogers KL, Leis A, Dewson G, Glukhova A, Komander D. Gan ZY, et al. Among authors: geoghegan nd. Nature. 2022 Feb;602(7896):328-335. doi: 10.1038/s41586-021-04340-2. Epub 2021 Dec 21. Nature. 2022. PMID: 34933320 Free PMC article.
Publisher Correction: Activation mechanism of PINK1.
Gan ZY, Callegari S, Cobbold SA, Cotton TR, Mlodzianoski MJ, Schubert AF, Geoghegan ND, Rogers KL, Leis A, Dewson G, Glukhova A, Komander D. Gan ZY, et al. Among authors: geoghegan nd. Nature. 2022 Mar;603(7903):E33. doi: 10.1038/s41586-022-04591-7. Nature. 2022. PMID: 35293391 Free PMC article. No abstract available.
Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission.
Lopaticki S, McConville R, John A, Geoghegan N, Mohamed SD, Verzier L, Steel RWJ, Evelyn C, O'Neill MT, Soler NM, Scott NE, Rogers KL, Goddard-Borger ED, Boddey JA. Lopaticki S, et al. Nat Commun. 2022 Jul 29;13(1):4400. doi: 10.1038/s41467-022-32076-8. Nat Commun. 2022. PMID: 35906227 Free PMC article.
20 results