Taylor S - Search Results

1

Capturing Differences in the Regulation of LRRK2 Dynamics and Conformational States by Small Molecule Kinase Inhibitors.

Weng JH, Ma W, Wu J, Sharma PK, Silletti S, McCammon JA, Taylor S. Weng JH, et al. Among authors: taylor s. ACS Chem Biol. 2023 Apr 21;18(4):810-821. doi: 10.1021/acschembio.2c00868. Epub 2023 Apr 12. ACS Chem Biol. 2023. PMID: 37043829 Free PMC article.

2

Determinants of ligand binding to cAMP-dependent protein kinase.

Hünenberger PH, Helms V, Narayana N, Taylor SS, McCammon JA. Hünenberger PH, et al. Among authors: taylor ss. Biochemistry. 1999 Feb 23;38(8):2358-66. doi: 10.1021/bi982064g. Biochemistry. 1999. PMID: 10029529

3

Computational analysis of PKA-balanol interactions.

Wong CF, Hünenberger PH, Akamine P, Narayana N, Diller T, McCammon JA, Taylor S, Xuong NH. Wong CF, et al. Among authors: taylor s. J Med Chem. 2001 May 10;44(10):1530-9. doi: 10.1021/jm000443d. J Med Chem. 2001. PMID: 11334563

4

Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure.

Akamine P, Madhusudan, Wu J, Xuong NH, Ten Eyck LF, Taylor SS. Akamine P, et al. Among authors: taylor ss. J Mol Biol. 2003 Mar 14;327(1):159-71. doi: 10.1016/s0022-2836(02)01446-8. J Mol Biol. 2003. PMID: 12614615

5

Crystal structures of RIalpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP.

Wu J, Jones JM, Nguyen-Huu X, Ten Eyck LF, Taylor SS. Wu J, et al. Among authors: taylor ss. Biochemistry. 2004 Jun 1;43(21):6620-9. doi: 10.1021/bi0302503. Biochemistry. 2004. PMID: 15157095

6

RIalpha subunit of PKA: a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B.

Wu J, Brown S, Xuong NH, Taylor SS. Wu J, et al. Among authors: taylor ss. Structure. 2004 Jun;12(6):1057-65. doi: 10.1016/j.str.2004.03.022. Structure. 2004. PMID: 15274925 Free article.

7

Dynamics of signaling by PKA.

Taylor SS, Kim C, Vigil D, Haste NM, Yang J, Wu J, Anand GS. Taylor SS, et al. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):25-37. doi: 10.1016/j.bbapap.2005.08.024. Epub 2005 Sep 22. Biochim Biophys Acta. 2005. PMID: 16214430 Review.

8

Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.

Wu J, Yang J, Kannan N, Madhusudan, Xuong NH, Ten Eyck LF, Taylor SS. Wu J, et al. Among authors: taylor ss. Protein Sci. 2005 Nov;14(11):2871-9. doi: 10.1110/ps.051715205. Protein Sci. 2005. PMID: 16253959 Free PMC article.

9

A simple electrostatic switch important in the activation of type I protein kinase A by cyclic AMP.

Vigil D, Lin JH, Sotriffer CA, Pennypacker JK, McCammon JA, Taylor SS. Vigil D, et al. Among authors: taylor ss. Protein Sci. 2006 Jan;15(1):113-21. doi: 10.1110/ps.051723606. Epub 2005 Dec 1. Protein Sci. 2006. PMID: 16322564 Free PMC article.

10

Dynamic binding of PKA regulatory subunit RI alpha.

Gullingsrud J, Kim C, Taylor SS, McCammon JA. Gullingsrud J, et al. Among authors: taylor ss. Structure. 2006 Jan;14(1):141-9. doi: 10.1016/j.str.2005.09.019. Structure. 2006. PMID: 16407073 Free article.

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