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Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies.
Sabatino M, Hu J, Sommariva M, Gautam S, Fellowes V, Hocker JD, Dougherty S, Qin H, Klebanoff CA, Fry TJ, Gress RE, Kochenderfer JN, Stroncek DF, Ji Y, Gattinoni L. Sabatino M, et al. Among authors: hocker jd. Blood. 2016 Jul 28;128(4):519-28. doi: 10.1182/blood-2015-11-683847. Epub 2016 May 25. Blood. 2016. PMID: 27226436 Free PMC article.
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation.
Kubo N, Ishii H, Xiong X, Bianco S, Meitinger F, Hu R, Hocker JD, Conte M, Gorkin D, Yu M, Li B, Dixon JR, Hu M, Nicodemi M, Zhao H, Ren B. Kubo N, et al. Among authors: hocker jd. Nat Struct Mol Biol. 2021 Feb;28(2):152-161. doi: 10.1038/s41594-020-00539-5. Epub 2021 Jan 4. Nat Struct Mol Biol. 2021. PMID: 33398174 Free PMC article.
A single-cell atlas of chromatin accessibility in the human genome.
Zhang K, Hocker JD, Miller M, Hou X, Chiou J, Poirion OB, Qiu Y, Li YE, Gaulton KJ, Wang A, Preissl S, Ren B. Zhang K, et al. Among authors: hocker jd. Cell. 2021 Nov 24;184(24):5985-6001.e19. doi: 10.1016/j.cell.2021.10.024. Epub 2021 Nov 12. Cell. 2021. PMID: 34774128 Free PMC article.
Improved epicardial cardiac fibroblast generation from iPSCs.
Whitehead AJ, Hocker JD, Ren B, Engler AJ. Whitehead AJ, et al. Among authors: hocker jd. J Mol Cell Cardiol. 2022 Mar;164:58-68. doi: 10.1016/j.yjmcc.2021.11.011. Epub 2021 Nov 24. J Mol Cell Cardiol. 2022. PMID: 34826415 Free PMC article.
Cardiac cell type-specific gene regulatory programs and disease risk association.
Hocker JD, Poirion OB, Zhu F, Buchanan J, Zhang K, Chiou J, Wang TM, Zhang Q, Hou X, Li YE, Zhang Y, Farah EN, Wang A, McCulloch AD, Gaulton KJ, Ren B, Chi NC, Preissl S. Hocker JD, et al. Sci Adv. 2021 May 14;7(20):eabf1444. doi: 10.1126/sciadv.abf1444. Print 2021 May. Sci Adv. 2021. PMID: 33990324 Free PMC article.
AP-1 signaling modulates cardiac fibroblast stress responses.
Whitehead AJ, Atcha H, Hocker JD, Ren B, Engler AJ. Whitehead AJ, et al. Among authors: hocker jd. J Cell Sci. 2023 Dec 1;136(23):jcs261152. doi: 10.1242/jcs.261152. Epub 2023 Dec 15. J Cell Sci. 2023. PMID: 37994565
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate.
Ji Y, Fioravanti J, Zhu W, Wang H, Wu T, Hu J, Lacey NE, Gautam S, Le Gall JB, Yang X, Hocker JD, Escobar TM, He S, Dell'Orso S, Hawk NV, Kapoor V, Telford WG, Di Croce L, Muljo SA, Zhang Y, Sartorelli V, Gattinoni L. Ji Y, et al. Among authors: hocker jd. Nat Commun. 2019 May 14;10(1):2157. doi: 10.1038/s41467-019-09882-8. Nat Commun. 2019. PMID: 31089138 Free PMC article.
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity.
Gautam S, Fioravanti J, Zhu W, Le Gall JB, Brohawn P, Lacey NE, Hu J, Hocker JD, Hawk NV, Kapoor V, Telford WG, Gurusamy D, Yu Z, Bhandoola A, Xue HH, Roychoudhuri R, Higgs BW, Restifo NP, Bender TP, Ji Y, Gattinoni L. Gautam S, et al. Among authors: hocker jd. Nat Immunol. 2019 Mar;20(3):337-349. doi: 10.1038/s41590-018-0311-z. Epub 2019 Feb 18. Nat Immunol. 2019. PMID: 30778251 Free PMC article.
13 results