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Next Generation Exon 51 Skipping Antisense Oligonucleotides for Duchenne Muscular Dystrophy.
Nucleic Acid Ther. 2023 Jun;33(3):193-208. doi: 10.1089/nat.2022.0063. Epub 2023 Apr 10.
Nucleic Acid Ther. 2023.
PMID: 37036788
Free PMC article.
Using a State-of-the-Art Toolbox to Evaluate Molecular and Functional Readouts of Antisense Oligonucleotide-Induced Exon Skipping in mdx Mice.
Datson NA, Bijl S, Janson A, Testerink J, van den Eijnde R, Weij R, Puoliväli J, Lehtimäki K, Bragge T, Ahtoniemi T, van Deutekom JC.
Datson NA, et al. Among authors: weij r.
Nucleic Acid Ther. 2020 Feb;30(1):50-65. doi: 10.1089/nat.2019.0824. Epub 2019 Dec 10.
Nucleic Acid Ther. 2020.
PMID: 31821107
Free PMC article.
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Exploring the frontiers of therapeutic exon skipping for Duchenne muscular dystrophy by double targeting within one or multiple exons.
Aartsma-Rus A, Kaman WE, Weij R, den Dunnen JT, van Ommen GJ, van Deutekom JC.
Aartsma-Rus A, et al. Among authors: weij r.
Mol Ther. 2006 Sep;14(3):401-7. doi: 10.1016/j.ymthe.2006.02.022. Epub 2006 Jun 6.
Mol Ther. 2006.
PMID: 16753346
Free article.
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Suppression of Mutant Protein Expression in SCA3 and SCA1 Mice Using a CAG Repeat-Targeting Antisense Oligonucleotide.
Kourkouta E, Weij R, González-Barriga A, Mulder M, Verheul R, Bosgra S, Groenendaal B, Puoliväli J, Toivanen J, van Deutekom JCT, Datson NA.
Kourkouta E, et al. Among authors: weij r.
Mol Ther Nucleic Acids. 2019 Sep 6;17:601-614. doi: 10.1016/j.omtn.2019.07.004. Epub 2019 Jul 19.
Mol Ther Nucleic Acids. 2019.
PMID: 31394429
Free PMC article.
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Detailed genetic and functional analysis of the hDMDdel52/mdx mouse model.
Yavas A, Weij R, van Putten M, Kourkouta E, Beekman C, Puoliväli J, Bragge T, Ahtoniemi T, Knijnenburg J, Hoogenboom ME, Ariyurek Y, Aartsma-Rus A, van Deutekom J, Datson N.
Yavas A, et al. Among authors: weij r.
PLoS One. 2020 Dec 23;15(12):e0244215. doi: 10.1371/journal.pone.0244215. eCollection 2020.
PLoS One. 2020.
PMID: 33362201
Free PMC article.
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The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain.
Datson NA, González-Barriga A, Kourkouta E, Weij R, van de Giessen J, Mulders S, Kontkanen O, Heikkinen T, Lehtimäki K, van Deutekom JC.
Datson NA, et al. Among authors: weij r.
PLoS One. 2017 Feb 9;12(2):e0171127. doi: 10.1371/journal.pone.0171127. eCollection 2017.
PLoS One. 2017.
PMID: 28182673
Free PMC article.
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Elevated Southern Hemisphere moisture availability during glacial periods.
Weij R, Sniderman JMK, Woodhead JD, Hellstrom JC, Brown JR, Drysdale RN, Reed E, Bourne S, Gordon J.
Weij R, et al.
Nature. 2024 Feb;626(7998):319-326. doi: 10.1038/s41586-023-06989-3. Epub 2024 Feb 7.
Nature. 2024.
PMID: 38326596
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Tufas indicate prolonged periods of water availability linked to human occupation in the southern Kalahari.
von der Meden J, Pickering R, Schoville BJ, Green H, Weij R, Hellstrom J, Greig A, Woodhead J, Khumalo W, Wilkins J.
von der Meden J, et al. Among authors: weij r.
PLoS One. 2022 Jul 20;17(7):e0270104. doi: 10.1371/journal.pone.0270104. eCollection 2022.
PLoS One. 2022.
PMID: 35857764
Free PMC article.
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