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Synthesis and anti-Alzheimer potential of novel α-amino phosphonate derivatives and probing their molecular interaction mechanism with acetylcholinesterase.
Yelamanda Rao K, Jeelan Basha S, Monika K, Sreelakshmi M, Sivakumar I, Mallikarjuna G, Yadav RM, Kumar S, Subramanyam R, Damu AG. Yelamanda Rao K, et al. Among authors: subramanyam r. Eur J Med Chem. 2023 May 5;253:115288. doi: 10.1016/j.ejmech.2023.115288. Epub 2023 Mar 30. Eur J Med Chem. 2023. PMID: 37031527
New Flavone-Cyanoacetamide Hybrids with a Combination of Cholinergic, Antioxidant, Modulation of β-Amyloid Aggregation, and Neuroprotection Properties as Innovative Multifunctional Therapeutic Candidates for Alzheimer's Disease and Unraveling Their Mechanism of Action with Acetylcholinesterase.
Basha SJ, Mohan P, Yeggoni DP, Babu ZR, Kumar PB, Rao AD, Subramanyam R, Damu AG. Basha SJ, et al. Among authors: subramanyam r. Mol Pharm. 2018 Jun 4;15(6):2206-2223. doi: 10.1021/acs.molpharmaceut.8b00041. Epub 2018 May 24. Mol Pharm. 2018. PMID: 29745222
Synthesis and biological evaluation of flavone-8-acrylamide derivatives as potential multi-target-directed anti Alzheimer agents and investigation of binding mechanism with acetylcholinesterase.
Shaik JB, Yeggoni DP, Kandrakonda YR, Penumala M, Zinka RB, Kotapati KV, Darla MM, Ampasala DR, Subramanyam R, Amooru DG. Shaik JB, et al. Among authors: subramanyam r. Bioorg Chem. 2019 Jul;88:102960. doi: 10.1016/j.bioorg.2019.102960. Epub 2019 May 3. Bioorg Chem. 2019. PMID: 31102808
193 results