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Neuroprotective actions of a fatty acid nitroalkene in Parkinson's disease.
NPJ Parkinsons Dis. 2023 Apr 7;9(1):55. doi: 10.1038/s41531-023-00502-3.
NPJ Parkinsons Dis. 2023.
PMID: 37029127
Free PMC article.
LRRK2 activation in idiopathic Parkinson's disease.
Di Maio R, Hoffman EK, Rocha EM, Keeney MT, Sanders LH, De Miranda BR, Zharikov A, Van Laar A, Stepan AF, Lanz TA, Kofler JK, Burton EA, Alessi DR, Hastings TG, Greenamyre JT.
Di Maio R, et al. Among authors: keeney mt.
Sci Transl Med. 2018 Jul 25;10(451):eaar5429. doi: 10.1126/scitranslmed.aar5429.
Sci Transl Med. 2018.
PMID: 30045977
Free PMC article.
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LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease.
Rocha EM, De Miranda BR, Castro S, Drolet R, Hatcher NG, Yao L, Smith SM, Keeney MT, Di Maio R, Kofler J, Hastings TG, Greenamyre JT.
Rocha EM, et al. Among authors: keeney mt.
Neurobiol Dis. 2020 Feb;134:104626. doi: 10.1016/j.nbd.2019.104626. Epub 2019 Oct 13.
Neurobiol Dis. 2020.
PMID: 31618685
Free PMC article.
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Measurement of LRRK2 Kinase Activity by Proximity Ligation Assay.
Keeney MT, Hoffman EK, Greenamyre TJ, Di Maio R.
Keeney MT, et al.
Bio Protoc. 2021 Sep 5;11(17):e4140. doi: 10.21769/BioProtoc.4140. eCollection 2021 Sep 5.
Bio Protoc. 2021.
PMID: 34604446
Free PMC article.
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LRRK2 and idiopathic Parkinson's disease.
Rocha EM, Keeney MT, Di Maio R, De Miranda BR, Greenamyre JT.
Rocha EM, et al. Among authors: keeney mt.
Trends Neurosci. 2022 Mar;45(3):224-236. doi: 10.1016/j.tins.2021.12.002. Epub 2022 Jan 4.
Trends Neurosci. 2022.
PMID: 34991886
Free PMC article.
Review.
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NADPH oxidase 2 activity in Parkinson's disease.
Keeney MT, Hoffman EK, Farmer K, Bodle CR, Fazzari M, Zharikov A, Castro SL, Hu X, Mortimer A, Kofler JK, Cifuentes-Pagano E, Pagano PJ, Burton EA, Hastings TG, Greenamyre JT, Di Maio R.
Keeney MT, et al.
Neurobiol Dis. 2022 Aug;170:105754. doi: 10.1016/j.nbd.2022.105754. Epub 2022 May 13.
Neurobiol Dis. 2022.
PMID: 35577065
Free PMC article.
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The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR, Carr SA, Lindquist S, De Jager PL, Bartel DP, Myers CL, Greenamyre JT, Feany MB, Sunyaev SR, Chung CY, Khurana V.
Hallacli E, et al. Among authors: keeney mt.
Cell. 2022 Jun 9;185(12):2035-2056.e33. doi: 10.1016/j.cell.2022.05.008.
Cell. 2022.
PMID: 35688132
Free PMC article.
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Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy.
Van Laar AD, Webb KR, Keeney MT, Van Laar VS, Zharikov A, Burton EA, Hastings TG, Glajch KE, Hirst WD, Greenamyre JT, Rocha EM.
Van Laar AD, et al. Among authors: keeney mt.
NPJ Parkinsons Dis. 2023 Aug 11;9(1):121. doi: 10.1038/s41531-023-00561-6.
NPJ Parkinsons Dis. 2023.
PMID: 37567894
Free PMC article.
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