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Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes.
Prodani C, Irvine EE, Sardini A, Gleneadie HJ, Dimond A, Van de Pette M, John R, Kokkinou M, Howes O, Withers DJ, Ungless MA, Merkenschlager M, Fisher AG. Prodani C, et al. Among authors: sardini a. Sci Rep. 2024 Apr 12;14(1):8528. doi: 10.1038/s41598-024-59083-7. Sci Rep. 2024. PMID: 38609446 Free PMC article.
Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss.
Hope DCD, Hinds CE, Lopes T, Vincent ML, Shrewsbury JV, Yu ATC, Davies I, Scott R, Jones B, Murphy KG, Minnion JS, Sardini A, Carling D, Lutz TA, Bloom SR, Tan TMM, Owen BM. Hope DCD, et al. Among authors: sardini a. Cell Rep Med. 2022 Nov 15;3(11):100810. doi: 10.1016/j.xcrm.2022.100810. Cell Rep Med. 2022. PMID: 36384093 Free PMC article.
Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice.
Van de Pette M, Dimond A, Galvão AM, Millership SJ, To W, Prodani C, McNamara G, Bruno L, Sardini A, Webster Z, McGinty J, French PMW, Uren AG, Castillo-Fernandez J, Watkinson W, Ferguson-Smith AC, Merkenschlager M, John RM, Kelsey G, Fisher AG. Van de Pette M, et al. Among authors: sardini a. Nat Commun. 2022 May 5;13(1):2464. doi: 10.1038/s41467-022-30022-2. Nat Commun. 2022. PMID: 35513363 Free PMC article.
AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue.
Pollard AE, Martins L, Muckett PJ, Khadayate S, Bornot A, Clausen M, Admyre T, Bjursell M, Fiadeiro R, Wilson L, Whilding C, Kotiadis VN, Duchen MR, Sutton D, Penfold L, Sardini A, Bohlooly-Y M, Smith DM, Read JA, Snowden MA, Woods A, Carling D. Pollard AE, et al. Among authors: sardini a. Nat Metab. 2019 Mar;1(3):340-349. doi: 10.1038/s42255-019-0036-9. Epub 2019 Feb 25. Nat Metab. 2019. PMID: 30887000 Free PMC article. No abstract available.
45 results