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Study protocol of a phase 2, randomised, placebo-controlled, double-blind, adaptive, parallel group clinical study to evaluate the efficacy and safety of recombinant alpha-1-microglobulin in subjects at high risk for acute kidney injury following open-chest cardiac surgery (AKITA trial).
Mazer CD, Siadati-Fini N, Boehm J, Wirth F, Myjavec A, Brown CD, Koyner JL, Boening A, Engelman DT, Larsson TE, Renfurm R, de Varennes B, Noiseux N, Thielmann M, Lamy A, Laflamme M, von Groote T, Ronco C, Zarbock A. Mazer CD, et al. Among authors: thielmann m. BMJ Open. 2023 Apr 6;13(4):e068363. doi: 10.1136/bmjopen-2022-068363. BMJ Open. 2023. PMID: 37024249 Free PMC article.
Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study.
Thielmann M, Corteville D, Szabo G, Swaminathan M, Lamy A, Lehner LJ, Brown CD, Noiseux N, Atta MG, Squiers EC, Erlich S, Rothenstein D, Molitoris B, Mazer CD. Thielmann M, et al. Circulation. 2021 Oct 5;144(14):1133-1144. doi: 10.1161/CIRCULATIONAHA.120.053029. Epub 2021 Sep 3. Circulation. 2021. PMID: 34474590 Free PMC article. Clinical Trial.
Thrombophilia in cardiac surgery--patients with protein S deficiency.
Massoudy P, Thielmann M, Müller-Beissenhirtz H, Aleksic I, Marggraf G, Dietrich W, Jakob H. Massoudy P, et al. Among authors: thielmann m. Ann Thorac Surg. 2006 Dec;82(6):2187-91. doi: 10.1016/j.athoracsur.2006.06.066. Ann Thorac Surg. 2006. PMID: 17126133
Incidence, predictors, origin and prevention of early and late neurological events after transcatheter aortic valve implantation (TAVI): a comprehensive review of current data.
Kahlert P, Al-Rashid F, Plicht B, Hildebrandt H, Patsalis P, Chilali KE, Wendt D, Thielmann M, Bergmann L, Kottenberg E, Schlamann M, Eggebrecht H, Jakob H, Heusch G, Konorza T, Erbel R. Kahlert P, et al. Among authors: thielmann m. J Thromb Thrombolysis. 2013 May;35(4):436-49. doi: 10.1007/s11239-012-0863-y. J Thromb Thrombolysis. 2013. PMID: 23292438 Review.
No protection of heart, kidneys and brain by remote ischemic preconditioning before transfemoral transcatheter aortic valve implantation: Interim-analysis of a randomized single-blinded, placebo-controlled, single-center trial.
Kahlert P, Hildebrandt HA, Patsalis PC, Al-Rashid F, Jánosi RA, Nensa F, Schlosser TW, Schlamann M, Wendt D, Thielmann M, Kottenberg E, Frey U, Neuhäuser M, Forsting M, Jakob HG, Rassaf T, Peters J, Heusch G, Kleinbongard P. Kahlert P, et al. Among authors: thielmann m. Int J Cardiol. 2017 Mar 15;231:248-254. doi: 10.1016/j.ijcard.2016.12.005. Epub 2016 Dec 6. Int J Cardiol. 2017. PMID: 27940009
Cytokine Hemoadsorption During Cardiac Surgery Versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results From a Multicenter Randomized Controlled Trial.
Diab M, Lehmann T, Bothe W, Akhyari P, Platzer S, Wendt D, Deppe AC, Strauch J, Hagel S, Günther A, Faerber G, Sponholz C, Franz M, Scherag A, Velichkov I, Silaschi M, Fassl J, Hofmann B, Lehmann S, Schramm R, Fritz G, Szabo G, Wahlers T, Matschke K, Lichtenberg A, Pletz MW, Gummert JF, Beyersdorf F, Hagl C, Borger MA, Bauer M, Brunkhorst FM, Doenst T; REMOVE Trial Investigators*. Diab M, et al. Circulation. 2022 Mar 29;145(13):959-968. doi: 10.1161/CIRCULATIONAHA.121.056940. Epub 2022 Feb 25. Circulation. 2022. PMID: 35213213 Clinical Trial.
246 results