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Study protocol of a phase 2, randomised, placebo-controlled, double-blind, adaptive, parallel group clinical study to evaluate the efficacy and safety of recombinant alpha-1-microglobulin in subjects at high risk for acute kidney injury following open-chest cardiac surgery (AKITA trial).
Mazer CD, Siadati-Fini N, Boehm J, Wirth F, Myjavec A, Brown CD, Koyner JL, Boening A, Engelman DT, Larsson TE, Renfurm R, de Varennes B, Noiseux N, Thielmann M, Lamy A, Laflamme M, von Groote T, Ronco C, Zarbock A. Mazer CD, et al. BMJ Open. 2023 Apr 6;13(4):e068363. doi: 10.1136/bmjopen-2022-068363. BMJ Open. 2023. PMID: 37024249 Free PMC article.
Acute kidney injury after cardiac surgery: focus on modifiable risk factors.
Karkouti K, Wijeysundera DN, Yau TM, Callum JL, Cheng DC, Crowther M, Dupuis JY, Fremes SE, Kent B, Laflamme C, Lamy A, Legare JF, Mazer CD, McCluskey SA, Rubens FD, Sawchuk C, Beattie WS. Karkouti K, et al. Among authors: mazer cd. Circulation. 2009 Feb 3;119(4):495-502. doi: 10.1161/CIRCULATIONAHA.108.786913. Epub 2009 Jan 19. Circulation. 2009. PMID: 19153273
Randomised trial of mitral valve repair with leaflet resection versus leaflet preservation on functional mitral stenosis (The CAMRA CardioLink-2 Trial).
Chan V, Chu MWA, Leong-Poi H, Latter DA, Hall J, Thorpe KE, de Varennes BE, Quan A, Tsang W, Dhingra N, Yared K, Teoh H, Chu FV, Chan KL, Mesana TG, Connelly KA, Ruel M, Jüni P, Mazer CD, Verma S. Chan V, et al. Among authors: mazer cd. BMJ Open. 2017 May 30;7(5):e015032. doi: 10.1136/bmjopen-2016-015032. BMJ Open. 2017. PMID: 28566364 Free PMC article. Clinical Trial.
Defining clinically important perioperative blood loss and transfusion for the Standardised Endpoints for Perioperative Medicine (StEP) collaborative: a protocol for a scoping review.
Bartoszko J, Vorobeichik L, Jayarajah M, Karkouti K, Klein AA, Lamy A, Mazer CD, Murphy M, Richards T, Englesakis M, Myles PS, Wijeysundera DN. Bartoszko J, et al. Among authors: mazer cd. BMJ Open. 2017 Jun 30;7(6):e016743. doi: 10.1136/bmjopen-2017-016743. BMJ Open. 2017. PMID: 28667227 Free PMC article. Review.
Allogeneic Mesenchymal Stem Cells for Treatment of AKI after Cardiac Surgery.
Swaminathan M, Stafford-Smith M, Chertow GM, Warnock DG, Paragamian V, Brenner RM, Lellouche F, Fox-Robichaud A, Atta MG, Melby S, Mehta RL, Wald R, Verma S, Mazer CD; ACT-AKI investigators. Swaminathan M, et al. Among authors: mazer cd. J Am Soc Nephrol. 2018 Jan;29(1):260-267. doi: 10.1681/ASN.2016101150. Epub 2017 Oct 16. J Am Soc Nephrol. 2018. PMID: 29038286 Free PMC article. Clinical Trial.
Safety of a Restrictive versus Liberal Approach to Red Blood Cell Transfusion on the Outcome of AKI in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial.
Garg AX, Badner N, Bagshaw SM, Cuerden MS, Fergusson DA, Gregory AJ, Hall J, Hare GMT, Khanykin B, McGuinness S, Parikh CR, Roshanov PS, Shehata N, Sontrop JM, Syed S, Tagarakis GI, Thorpe KE, Verma S, Wald R, Whitlock RP, Mazer CD; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group. Garg AX, et al. Among authors: mazer cd. J Am Soc Nephrol. 2019 Jul;30(7):1294-1304. doi: 10.1681/ASN.2019010004. Epub 2019 Jun 20. J Am Soc Nephrol. 2019. PMID: 31221679 Free PMC article. Clinical Trial.
Randomized, Controlled Trial Comparing Mitral Valve Repair With Leaflet Resection Versus Leaflet Preservation on Functional Mitral Stenosis: The CAMRA CardioLink-2 Study.
Chan V, Mazer CD, Ali FM, Quan A, Ruel M, de Varennes BE, Gregory AJ, Bouchard D, Whitlock RP, Chu MWA, Dokollari A, Mesana T, Bhatt DL, Latter DA, Zuo F, Tsang W, Teoh H, Jüni P, Leong-Poi H, Verma S. Chan V, et al. Among authors: mazer cd. Circulation. 2020 Oct 6;142(14):1342-1350. doi: 10.1161/CIRCULATIONAHA.120.046853. Epub 2020 Oct 5. Circulation. 2020. PMID: 33017212 Clinical Trial.
Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke.
Whitlock RP, Belley-Cote EP, Paparella D, Healey JS, Brady K, Sharma M, Reents W, Budera P, Baddour AJ, Fila P, Devereaux PJ, Bogachev-Prokophiev A, Boening A, Teoh KHT, Tagarakis GI, Slaughter MS, Royse AG, McGuinness S, Alings M, Punjabi PP, Mazer CD, Folkeringa RJ, Colli A, Avezum Á, Nakamya J, Balasubramanian K, Vincent J, Voisine P, Lamy A, Yusuf S, Connolly SJ; LAAOS III Investigators. Whitlock RP, et al. Among authors: mazer cd. N Engl J Med. 2021 Jun 3;384(22):2081-2091. doi: 10.1056/NEJMoa2101897. Epub 2021 May 15. N Engl J Med. 2021. PMID: 33999547 Clinical Trial.
Effect of Continuous Electrocardiogram Monitoring on Detection of Undiagnosed Atrial Fibrillation After Hospitalization for Cardiac Surgery: A Randomized Clinical Trial.
Ha ACT, Verma S, Mazer CD, Quan A, Yanagawa B, Latter DA, Yau TM, Jacques F, Brown CD, Singal RK, Yamashita MH, Saha T, Teoh KH, Lam BK, Deyell MW, Wilson M, Hibino M, Cheung CC, Kosmopoulos A, Garg V, Brodutch S, Teoh H, Zuo F, Thorpe KE, Jüni P, Bhatt DL, Verma A; SEARCH AF CardioLink-1 Investigators. Ha ACT, et al. Among authors: mazer cd. JAMA Netw Open. 2021 Aug 2;4(8):e2121867. doi: 10.1001/jamanetworkopen.2021.21867. JAMA Netw Open. 2021. PMID: 34448866 Free PMC article. Clinical Trial.
305 results