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APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles.
Ferrari-Souza JP, Lussier FZ, Leffa DT, Therriault J, Tissot C, Bellaver B, Ferreira PCL, Malpetti M, Wang YT, Povala G, Benedet AL, Ashton NJ, Chamoun M, Servaes S, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, O'Brien JT, Rowe JB, Cohen AD, Lopez OL, Tudorascu DL, Karikari TK, Klunk WE, Villemagne VL, Soucy JP, Gauthier S, Souza DO, Zetterberg H, Blennow K, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Among authors: pascoal ta. Sci Adv. 2023 Apr 5;9(14):eade1474. doi: 10.1126/sciadv.ade1474. Epub 2023 Apr 5. Sci Adv. 2023. PMID: 37018391 Free PMC article.
Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating.
Favier M, Janickova H, Justo D, Kljakic O, Runtz L, Natsheh JY, Pascoal TA, Germann J, Gallino D, Kang JI, Meng XQ, Antinora C, Raulic S, Jacobsen JP, Moquin L, Vigneault E, Gratton A, Caron MG, Duriez P, Brandon MP, Neto PR, Chakravarty MM, Herzallah MM, Gorwood P, Prado MA, Prado VF, El Mestikawy S. Favier M, et al. Among authors: pascoal ta. J Clin Invest. 2020 Dec 1;130(12):6616-6630. doi: 10.1172/JCI138532. J Clin Invest. 2020. PMID: 33164988 Free PMC article.
Epistasis analysis links immune cascades and cerebral amyloidosis.
Benedet AL, Labbe A, Lemay P, Zimmer ER, Pascoal TA, Leuzy A, Mathotaarachchi S, Mohades S, Shin M, Dionne-Laporte A, Beaudry T, Picard C, Gauthier S, Poirier J, Rouleau G, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Benedet AL, et al. Among authors: pascoal ta. J Neuroinflammation. 2015 Dec 1;12:227. doi: 10.1186/s12974-015-0436-z. J Neuroinflammation. 2015. PMID: 26626881 Free PMC article.
VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis.
Mathotaarachchi S, Wang S, Shin M, Pascoal TA, Benedet AL, Kang MS, Beaudry T, Fonov VS, Gauthier S, Labbe A, Rosa-Neto P. Mathotaarachchi S, et al. Among authors: pascoal ta. Front Neuroinform. 2016 Jun 15;10:20. doi: 10.3389/fninf.2016.00020. eCollection 2016. Front Neuroinform. 2016. PMID: 27378902 Free PMC article.
Synergistic interaction between amyloid and tau predicts the progression to dementia.
Pascoal TA, Mathotaarachchi S, Shin M, Benedet AL, Mohades S, Wang S, Beaudry T, Kang MS, Soucy JP, Labbe A, Gauthier S, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Pascoal TA, et al. Alzheimers Dement. 2017 Jun;13(6):644-653. doi: 10.1016/j.jalz.2016.11.005. Epub 2016 Dec 23. Alzheimers Dement. 2017. PMID: 28024995 Free article.
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain.
Ng KP, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MS, Shin M, Guiot MC, Guo Q, Harada R, Comley RA, Massarweh G, Soucy JP, Okamura N, Gauthier S, Rosa-Neto P. Ng KP, et al. Among authors: pascoal ta. Alzheimers Res Ther. 2017 Mar 31;9(1):25. doi: 10.1186/s13195-017-0253-y. Alzheimers Res Ther. 2017. PMID: 28359327 Free PMC article.
Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.
Ng KP, Pascoal TA, Mathotaarachchi S, Chung CO, Benedet AL, Shin M, Kang MS, Li X, Ba M, Kandiah N, Rosa-Neto P, Gauthier S; Alzheimer's Disease Neuroimaging Initiative. Ng KP, et al. Among authors: pascoal ta. Neurology. 2017 May 9;88(19):1814-1821. doi: 10.1212/WNL.0000000000003916. Epub 2017 Apr 12. Neurology. 2017. PMID: 28404803 Free PMC article.
Identifying incipient dementia individuals using machine learning and amyloid imaging.
Mathotaarachchi S, Pascoal TA, Shin M, Benedet AL, Kang MS, Beaudry T, Fonov VS, Gauthier S, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Mathotaarachchi S, et al. Among authors: pascoal ta. Neurobiol Aging. 2017 Nov;59:80-90. doi: 10.1016/j.neurobiolaging.2017.06.027. Epub 2017 Jul 11. Neurobiol Aging. 2017. PMID: 28756942 Free article.
150 results